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Opioid Dependence: A Clinical and Epidemiologic Approach

Opioid Dependence: A Clinical and Epidemiologic Approach

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A public health framework to examine the American opioid epidemic by categorizing the crisis through the epidemiologic triangle of agent, vector, and host. The agent refers to the specific pharmacology and biology of opioids, while the vector represents the prescribing practices and regulatory landscape governing medical professionals. A significant portion of the material focuses on the host, exploring the psychological, genetic, and social factors that contribute to addiction and physical dependence. To address the crisis, the author advocates for multimodal pain management that emphasizes non-opioid alternatives and psychological support. Ultimately, the source argues for a shift toward primary, secondary, and tertiary prevention strategies to foster "behavioral immunity" against drug misuse. Measures such as abuse-deterrent formulations and community naloxone distribution are presented as vital tools for reducing the virulence of the epidemic.

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