Jon Favreau and Tommy Vietor, co-hosts of Pod Save America and founders of Crooked Media, remember when politics felt hopeful. Their latest venture, after working for Obama, starting Crooked Media, and launching a slew of great ventures and podcasts, is a user's guide to American government: Democracy or Else: How to Save America in 10 Easy Steps. They are some of the most informed, level-headed, and hilarious political voices around, and their book is the antidote to feeling stressed out, beat down, and powerless over politics. You certainly don’t have to be a political junky to appreciate that!

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Seven years ago, Brian Wallch was diagnosed with ALS at just 37 years old. He and his wife, Sandra, found out on the day they brought their second daughter home from the hospital. Instead of passively accepting this new reality, the two decided to spearhead a patient driven movement. For Love and Life: No Ordinary Campaign is a new documentary on Amazon Prime, executive produced by Katie, that chronicles their love story, their demand to accelerate the rate of research, and their efforts to change legislation. Today on the podcast, we have a conversation with Brian, Sandra, Jeff MacGregor and Tim Rummel--two of the film's producers, and director Chris Burke. It is an episode you won't want to miss!

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Christina Applegate and Jamie-Lynn Sigler have been stars for decades–who can forget their turns in Anchorman and The Sopranos respectively?--but they share a sisterhood with each other: they’ve both been diagnosed with MS. Their podcast MeSsy is all about supporting each other and listeners through whatever curveballs life throws their way, and Katie was delighted to sit down on the interviewee side of the desk to discuss her activism around raising awareness for cancer–and also have some fun. From moving moments at Stand Up to Cancer benefits to stripper names and that one word everyone misuses this interview will have you in stitches.

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