Neuroscience in Hyperspace with Andrew Gallimore

In this episode we join pioneering psychedelic neuroscientist Andrew Gallimore (Website | X | Instagram | Substack) to probe the bewildering high-dimensional horizons of DMT research and their implications for our understanding of consciousness and the structure of reality. In his book Death by Astonishment, Gallimore argues DMT expands the brain’s “representational reach,” enabling perception of high-dimensional structures and apparent interaction with non-human “intelligent agents,” challenging standard accounts that treat the experience as mere hallucination, dreams, or Jungian archetypes. What new shapes will we—and our sciences—take as we integrate the intense strangeness of these experiences? How do we even begin to practice “truly psychedelic” science? And what insights might we be able to bring “home” to the Flatland where we spend most of our waking lives?Andrew has talked about this work in many, many other venues (his conversations with Jesse Michels and Danny Jones were especially good), so I wanted to carry the conversation into fresh terrain. Consider this episode the “200 level course”, or at least my best attempt ask a brilliant and provocative researcher some very complicated questions.Over our two hours together we discussed neuroimaging findings that challenge the “dream” and “archetype” interpretations of DMT phenomenology, how criticality and noise in complex systems inform our understanding of the psychedelic experience, and the methodological problems inherent in studying ontologically shocking experiences while maintaining scientific rigor. We also probed the philosophical implications of DMT research—such as the possibility that consciousness is more fundamental than matter—and the possible connections between DMT hyperspace and life in an era of advanced technology. Andrew also gave some context on the Noonautics research non-profit its partnership with the newly-launched Eleusis facility, a carefully-crafted venue for extended-state DMT work. But perhaps my favorite part of this conversation was spent in speculation, about how science and even language might evolve to meet the challenges presented by the ineffable high-dimensional reality that DMT reveals to us.✨ Like/Subscribe/Comment where you listen! YouTube • Spotify • Apple Podcasts✨ Become a member for our reading group, community calls, and years of members-only recordings — including the excellent raps we had recently on Alexander Douglas and Wendell Berry.✨ Become a founding member to access my online courses, including Jurassic Worlding and How To Live In The Future.✨ Browse and buy all of the books we discuss on the show at Bookshop.org✨ Music: “Scalar Reconfigurations” & “City of Jewels”✨ Contact me to collaborate or hire me as a consultantChapters00:00:00 Intro00:08:15 Gallimore’s Origin Story00:13:00 DMT as a Technology00:20:01 “Entities” & Methodological Problems00:29:06 World Models and EEG Clues00:36:57 Why The Psychedelic State is Not a Dream00:44:11 Noise, Criticality, and New Order00:47:50 The Temperature-Noise Motif00:52:47 Metabolism & Dimensionality00:53:47 The Cortex & Representational Reach00:57:44 Do We Need New Language to Study The DMT Realm?01:00:45 Is There Only The Subject?01:09:31 Psychedelic Science As Altered Observation01:17:34 DMTx & Eleusis Plans01:21:55 The Future of Transdimensional Research01:31:44 A Call for HumilityCited WorksNeural correlates of the DMT experience assessed with multivariate EEGby Christopher Timmerman et al.The Overfitted Brainby Erik HoelThe evolution of syntactic communicationby Martin Nowak et al.The Transcension Hypothesisby John SmartMiguel Fuentes & Marco Buongiorno Nardelli on Music, Emergence, and Societyfor Complexity PodcastAncient Extinction Events, Apocalyptic Cults, and DMT Entitieswith Michael on The Danny Jones PodcastOther MentionsStephen SzáraNick SandDonald HoffmanKarl FristonJordi RibaDavid ChalmersWilliam BurroughsJohn LillyPhil DickTerence McKennaRobert Anton WilsonJohn D. BarrowMentioned & Related Podcast Episodes This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit michaelgarfield.substack.com/subscribe