Neurology: Dr. Maurice Ferré on Insightec and the Rise of Focused Ultrasound

What if brain surgery no longer required a scalpel? Dr. Maurice Ferré, CEO of Insightec and co-founder of Mako Surgical, shares how MRI-guided focused ultrasound is redefining neurosurgery.

We discuss Insightec’s journey, the 2016 NEJM study that changed everything, and why focused ultrasound could transform treatment for tremor, Parkinson’s, and beyond.

Episode Breakdown

00:00 – Opening and welcome

01:02 – Introducing Dr. Maurice Ferré and Insightec

03:07 – From Mako Surgical to non-invasive brain surgery

05:44 – Focused ultrasound explained: sound as a scalpel

07:55 – First approvals for essential tremor and Parkinson’s

10:12 – Why 2016 NEJM study marked a turning point

12:20 – How MRgFUS compares to deep brain stimulation

14:18 – Expanding applications: neuromodulation, blood-brain barrier, oncology

16:42 – Patient experience: awake, no incision, same-day recovery

19:04 – Challenges: access, training, and reimbursement

21:37 – The milestone of 250M lives now covered

24:05 – Scaling to $100M revenue and global adoption

26:14 – The Prime system: simplifying workflow and expanding access

28:40 – Partnering with clinicians to drive real-world use

30:12 – Focus Forward: building the user community

32:20 – Where focused ultrasound is headed next

34:02 – Closing reflections and advice for future leaders

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