NEJM January 2026;Medical Management and Revascularization for Asymptomatic Carotid Stenosis

This research study evaluates the most effective way to treat patients with severely blocked carotid arteries who have not yet experienced symptoms like a stroke. Researchers compared the results of intensive medical management alone against combining that medication with surgical interventions like stenting or endarterectomy. The findings revealed that while surgical stenting significantly lowered the four-year risk of stroke or death compared to drugs alone, the benefits of traditional endarterectomy were not statistically significant. Ultimately, the trial suggests that integrating stenting with modern medicine offers a superior preventative strategy for maintaining long-term neurological health in high-risk patients.