Welcome to the Hot Topics podcast from NB Medical with Dr Neal Tucker. While everyone tries to unpick the new NHS 10-year plan, we focus on the here and now with three new pieces of research.

We kick off with two gems in the BJGP - first, examining whether anti-depressants actually help with insomnia, and second, whether anti-depressants cause postural hypotension in older people, and which may be the worst. Finally, we look at a good news story, with data publishing on a new treatment for cancers linked to mismatch repair genes.

References

BJGP Insomnia paper

BJGP Anti-Ds and postural hypotension paper

NEJM dMMR gene cancer therapy

www.nbmedical.com/podcast

Welcome to the Hot Topics podcast from NB Medical with Dr Neal Tucker. In this episode, we look at three new pieces of research with implications for general practice.

Firstly, can exercise prevent the recurrence of colorectal cancer? Short answer, yes. But how much exercise did you need to do, and what on earth is a MET?

Secondly, what are the concerns around low-dose amitriptyline use for IBS from patients and GPs? How can we aid the discussion?

Finally, can SLGT2 inhibitors improve liver disease? Is this the new treatment for our patients with MASLD (the condition formerly known as NAFLD?

References

NEJM Exercise and CRC

METs Wikipedia

BJGP IBS & amitriptyline prescribing

BMJ SGLT2i & MASLD

NB Blog MASLD: The rebrand you never heard of

www.nbmedical.com/podcast

Welcome to the Hot Topics podcast from NB Medical with Dr Neal Tucker. In this edition, we look at three new pieces of research.

First, in the BMJ, a paper exploring whether a GP-led psychological intervention can help PTSD symptoms in our patients after ICU. Could this also be successful for other forms of trauma?

Second, in the Lancet, research looking at whether semaglutide can improve walking distance in patients with diabetes and intermittent claudication.

Finally, in the BJGP, can a practice-led physical activity intervention improve symptoms in survivors of cancer? Will anyone actually want to do it? The answer, and who, may surprise you.

References

Poor by Katriona O'Sullivan

BMJ PTSD paper

Lancet GLP1ra and PAD

BJGP Physical activity and cancer survivors

Moving Medicine

www.nbmedical.com/podcast