Mutations

This episode dives into the world of genetics and mutations. We’re joined by two experts: Marc de Manuel (IBE) studying the mechanisms and evolutionary variation of mutations, and Donate Weghorn (CRG) developing computational models to predict mutation probability. Together, they shed light on cancer, inherited mutations across families, and the curious Peto’s paradox—why bigger, longer-lived animals aren’t necessarily more prone to cancer. We also step outside the lab to discuss careers in research: short-term versus tenure-track contracts for early-stage PIs, and whether institutions truly value the right qualities when it comes to promotion.

‘Science With a View’ a PRBB production:

• Script & presenter: Chris George
• Editing: Inés Fuentes
• Recording: Jordi Blanco & Rosa Camacho
• Post-production: Teo Grimalt
• Theme tune: Liam Colomer (voice-over, Alix Musset)