Can diabetes and weight loss drugs help with migraine relief? A new study suggests GLP-1 medications may significantly reduce migraine days. @ Molly O’Brien has more in this Migraine Minute News Update.

Read More: http://bit.ly/4kGN4eO

Image and license to use: Headache. 2025; 00: 1-8. http://bit.ly/47imNQO

Script: GLP-1s….a drug class widely used for diabetes and weight loss treatment, may also help migraine.

A small study published in Headache looked at liraglutide as an add-on treatment for unresponsive migraine in people with obesity who have tried at least two preventive migraine treatments. The study tracked 31 adults with high-frequency episodic or chronic migraine.

After taking a daily dose of the drug for three months, on average, they saw monthly headache days drop from about 20 to just under 11—a significant improvement. What may be surprising… is that the benefit came with insignificant weight loss.

A major study found that oral triptans work better for the acute treatment of migraine, than newer drugs. Molly O’Brien breaks it all down in this Migraine Minute News Update.

Read more: https://bit.ly/3Wu6ZnP

Images and License to use: BMJ 2024;386:e080107
http://bit.ly/4ljgU9x

Script: A major international study published in the British Medical Journal found triptans to be the most effective acute treatment for migraine.

Researchers analyzed 137 clinical trials involving nearly 90,000 adults… comparing 17 oral treatments. They looked at how many people were pain-free two hours post-dose and how many were still pain-free at 24 hours, as well as the safety and tolerability of the treatments.

They looked at how many people were pain-free at 2 hours and 24 hours, as well as the safety and tolerability of the treatments.

The top performer? Eletriptan — it was shown to be the most effective for both rapid and sustained pain relief. Other high performers included rizatriptan, sumatriptan, and zolmitriptan. Those four triptans consistently outperformed newer acute treatment options like lasmiditan, ubrogepant, and rimegepant.

These newer acute treatments worked about as well as acetaminophen and most non-steroidal anti-inflammatory drugs. Also, results showed that not all NSAIDs work the same for migraine.

Celebrating the Fourth of July with migraine is not easy. The holiday can be packed with sensory overload and migraine triggers. In this Migraine Minute, Molly O’Brien shares tips to help you enjoy the celebration while protecting your health. Check out our updated triggers webpage: https://bit.ly/4kFOZRf

Reference: https://pubmed.ncbi.nlm.nih.gov/19329386/

Script:
While the Fourth of July can be a fun holiday to celebrate in the States, it can be tough for folks with migraine. Why? Well, there are so many factors that can be stacked against you. Think about it, heat, big crowds, staying up late, BBQ foods and drinks that might have triggering ingredients…Not to mention the bright flashes and loud bangs of fireworks. Research even shows exposure to sulfur dioxide, a common byproduct of fireworks, may trigger migraine attacks. If you have migraine and still want to enjoy the holiday, here are some tips from our migraine community: Stay hydrated, wear ear plugs, watch fireworks from afar or skip all together, bring migraine safe food and drinks to your cook out, wear sunglasses or migraine glasses, and keep a consistent routine.

Don’t forget to check out AMD’s updated triggers page, where you can learn more about common migraine triggers and how to manage them.