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In this compelling episode of MedTech 101, host Rodney Moses sits down with RenovoRx CEO Shaun Bagai to explore the latest breakthroughs in cancer treatment. The conversation opens with a clear-eyed look at the challenges pancreatic cancer patients face, before diving into Shaun’s remarkable journey—from aspiring pre-med student to seasoned medtech leader—and the pivotal role engineering plays in redefining cancer care.

Rodney underscores the importance of pairing technological innovation with true patient-centric thinking, setting the tone for an insightful discussion on medtech’s ability to transform lives.

Shaun explains how RenovoRx is changing the treatment landscape through its patented localized therapy platform, designed to deliver chemotherapy directly to the tumor while reducing life-limiting systemic side effects. Their discussion highlights the development and impact of the RenovoCath catheter and the Trans-Arterial Micro-Perfusion (TAMP) system, technologies that enable precise, targeted drug delivery and bring renewed hope for improved outcomes.

Rodney and Shaun also touch on the contrast between the agility of startups and the slower pace of traditional medtech companies—using RenovoRx’s journey to a NASDAQ listing, without being acquired by a larger player, as a powerful example of strategic independence. The episode wraps with optimism about the future of oncology and the transformative potential of smarter drug-delivery systems.

Timestamp Summary

00:00 | Innovative Approach to Treating Pancreatic Cancer Locally
01:50 | Renovo Rx's Innovative Approach to Localized Chemotherapy Delivery
02:31 | From Medtronic to CEO: A Journey in Medical Innovation
05:28 | Leveraging Technology in Medicine for Widespread Impact
06:47 | RenovoRx's Unique Path in the Medtech Industry
12:39 | Innovative Localized Chemotherapy for Pancreatic Cancer Treatment
19:22 | Expanding Life-Saving Technology Beyond the US Market
21:02 | Innovative Delivery Systems for Pancreatic Cancer Treatment

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Viral Thakkar, COO of LungPacer Medical, joins Rodney on the MedTech 101 Podcast to discuss how cutting-edge innovation is reshaping ventilator technology. They unpack the limitations of traditional mechanical ventilation and its often-overlooked effects on the diaphragm. Viral shares insights into AeroPace, LungPacer’s breakthrough system that uses phrenic nerve stimulation to help patients breathe and recover more effectively.

The discussion dives into the real-world challenges of clinical adoption, the significance of FDA Breakthrough Designation, and what the future holds for ventilation care. Tune in to learn how this technology could redefine outcomes for ICU patients by reducing complications and accelerating recovery.

Timestamp
00:00 The Impact of Mechanical Ventilation on Diaphragm Health
02:02 From R&D to COO: Viral Thakkar's Medtech Journey
03:20 A Journey from Personal Tragedy to Medical Device Innovation
05:56 Ventilator-Induced Diaphragm Dysfunction and Its Consequences
11:38 Innovative Diaphragm Stimulation Technology for Improved Ventilation
15:45 Breakthrough Medical Device Designation and Market Challenges
19:27 Innovative Ventilation Technology Aims to Improve ICU Patient Outcomes

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Ben Tasker, is an AI expert who has transitioned from academia to the utilities sector, focusing on upskilling and reskilling the workforce for the AI era. He discusses his experience developing AI systems for student success prediction in education and cancer risk identification in healthcare.

The core themes are:

The importance of responsible and ethical AI practices as the technology rapidly advances
The challenges of getting buy-in from end-users (students, patients, employees) and integrating AI into existing workflows
The potential of AI to enable more personalized services, especially in healthcare and mental health
The need to balance the benefits of AI-powered personalization with concerns around privacy, transparency, and the risk of reinforcing biases

Overall, Ben emphasizes the critical role of human-centered design and stakeholder engagement in ensuring AI is implemented effectively and ethically across different industries.

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