Is All Psychosis The Same?
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The paper we discuss is BA Clementz et al. Identification of Psychosis Biotypes Using Brain-Based Biomarkers. Am J Psychiatry 2016; 173(4): 373-384.
Here's the paper Dr Toups mentions about depression, biotypes, and treatment response: AT Drysdale et al. Resting-state connectivity biomarkers define neurophysiological subtypes of depression. Nature Medicine 2017; 23: 28-28.
The discussion about psychiatric nosology has led to some heated discussions and received a bit of attention in the popular press. The New Yorker's take is here.
We are not the only the psychiatry podcast that has discussed these questions. There's also an excellent discussion on the first episode of the podcast Ten to the Fifteenth, which is produced by the National Neuroscience Curriculum Initiative.