In Episode 2 of Unlocking Antiarrhythmics From ABCs to Action, #HRStv host Deepthy Varghese, DNP, ACNP, FNP is joined by Jose L. Merino, MD, PhD to explore what it means to truly personalize antiarrhythmic drug (AAD) therapy across diverse patient populations. Together, they discuss real-world strategies for tailoring treatment based on age, comorbidities, arrhythmia type, and individual risk factors — highlighting how precision medicine is reshaping rhythm management. From dosing considerations to emerging research and clinical challenges, viewers will gain actionable insight to help optimize AAD use in varied care settings and deliver more confident, patient-centered treatment.

Stay tuned for Episode 3: Wearables and AADs: Next-Gen Rhythm Monitoring at Home

Additional Resources

https://academic.oup.com/europace/article/27/8/euaf076/8100306?login=true

https://www.jacc.org/doi/10.1016/j.jacep.2024.11.020

Want to explore more content? Catch the full video versions and more on our channel – [Heart Rhythm TV].

In this Breaking News conversation, #HRStv host Daniel M. Alyesh, MD, FHRS, is joined by Melanie Gunawardene, MD, FHRS, and Julian Chun, MD, to discuss a recent Circulation Research Letter describing life-threatening delayed myocardial ischemia and arrhythmias following PFA for AFib. They explore the proposed mechanisms and its correlation with the MANIFEST US study, as well as comparisons with thermal ablation data.

Additional Resources

Circulation. 2026;153:00–00. DOI: 10.1161/CIRCULATIONAHA.125.077983
Turagam, M, Aryana, A, Day, J. et al. Multicenter Study on the Safety of Pulsed Field Ablation in Over 40,000 Patients: MANIFEST-US. JACC. null2025, 0 (0)
Circ Arrhythm Electrophysiol. 2023;16:e011365. DOI: 10.1161/CIRCEP.122.011365

Want to explore more content? Catch the full video versions and more on our channel – [Heart Rhythm TV].

Unlocking Antiarrhythmics From ABCs to Action is a new 3-part series designed to strengthen foundational knowledge and support real-world clinical decision-making for allied professionals.

From the basics to advanced strategies, this episode breaks down antiarrhythmic drug classes, safety considerations, and how to personalize therapy across diverse patient populations — including the latest on outpatient sotalol and wearable heart monitoring.

#HRStv host Deepthy Varghese, DNP, ACNP, FNP is joined by Megan Labreck, PharmD, and Rachel Schreier, MSN, ACNP, APRN for a practical, clinically focused discussion to support confident patient care.

Stay tuned for Episodes 2 and 3:

Episode 2: Real-World Rhythm — Personalizing AADs Across Populations

Episode 3: Wearables and AADs: Next-Gen Rhythm Monitoring at Home

Additional Resources

https://academic.oup.com/europace/advance-article/doi/10.1093/europace/euaf076/8100306

https://www.jacc.org/doi/abs/10.1016/j.jacep.2024.11.020

https://www.jacc.org/doi/abs/10.1016/j.jacep.2024.10.003

https://www.sciencedirect.com/science/article/pii/S2666501824001478

Want to explore more content? Catch the full video versions and more on our channel – [Heart Rhythm TV].