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Grow Everything Biotech Podcast

Grow Everything Biotech Podcast

De: Messaginglab
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Grow Everything explores the world of biology as technology. Hosts Erum Khan and Karl Schmieder interview leaders and influencers biologizing industries with tools like synthetic biology, precision fermentation, bioprospecting, and more. These companies make biomaterials from waste, cosmetics that restore healthy hair and skin, and delicious cultivated foods in a bioreactor and so much more. Join us as we discuss the latest and greatest across biotech, engineered biology, entrepreneurship, and culture and how this transition is solving healthcare and climate change challenges.Messaginglab Ciencia Ciencias Biológicas
Episodios
  • 177. Dye Another Day (REPLAY): The New Way to Color Textiles with Colorifix's Orr Yarkoni
    Apr 17 2026
    In this replay episode of Grow Everything, Karl and Erum catch up after recent travel, reflect on a standout mainstream biotech article about biology reshaping the global chemical industry, and discuss why “tissue-on-a-chip” experiments in space matter for long-duration missions. They then kick off a deeper dive into bio-based dyes by revisiting their interview with Orr Yarkoni, co-founder and CEO of Colorifix, who explains how engineered microbes can both produce and directly deposit pigment onto textiles to dramatically reduce toxic chemistry, water use, and energy demand compared to conventional dyeing. The conversation covers why black and high-performance reds remain the hardest colors to replace, how Colorifix approaches scale-up through distributed on-site fermentation hardware, and what it takes to meet the real-world fastness and safety standards that brands and mills require.Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing?Learn more at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.messaginglab.com/groweverything⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Chapters:(00:00:00) Travel catch-up and what the hosts have been thinking about lately(00:05:30) Mainstream biotech gets it right: biology as “Mother Nature’s R&D lab” for the chemical industry(00:07:15) Artemis and why deep-space biology experiments matter(00:08:40) Project Hail Mary and communicating across radically different biology(00:12:55) Why this season is focusing on bio dyes, and why textiles are a key wedge industry(00:16:55) Interview begins: Orr’s background and the pivot from arsenic biosensing to dyeing(00:20:15) How conventional textile dyeing works, and why it is so chemically and water intensive(00:24:10) What Colorifix does differently: microbes that make dye and fix it onto fabric(00:27:10) Performance realities: lightfastness, washfastness, and why “green but fragile” is not sustainability(00:29:35) Finding pigments in nature, choosing the right biosynthetic routes, and translating them across materials(00:34:20) Who buys what: dye houses, mills, and how the business model works(00:36:55) Scaling fermentation the hard way: standardizing hardware and enabling on-site production(00:40:05) Hardware basics and the economics of bioreactors for commodity chemicals(00:44:05) Worker health, safer chemistry, and toxicity testing across the full process(00:46:05) Where you can find Colorifix in-market, and which materials are trending(00:49:00) Color priorities: why blue is easiest, and why black is the biggest challenge(00:51:15) Regulation tailwinds: why some black chemistries are being phased out(00:55:15) The future: bio-manufacturing everyday goods at scale(00:58:45) Orr’s film recommendation: The Man in the White Suit(01:00:00) Closing: upcoming live recording at DC Climate Week and SynBioBetaLinks and Resources:Colorifix 75. Dye Another Day: The New Way to Color Textiles with Colorifix's Orr YarkoniTracking the removal of Petroleum-based Food Dyes Food Safety and Health Concerns of Synthetic Food DyesNational Geographic Spider SilkArtemis Mission - Lunar FlybyDC Climate WeekSynBioBeta Pass - Discount code: Grow Everything Topics Covered:industrial biotech, synthetic biology, biomanufacturing, microbial fermentation, engineered microbes, sustainable textiles, bio-based dyes, textile dyeing process, green chemistryHave a question or comment? Message us here:Text or Call (804) 505-5553⁠⁠⁠⁠⁠⁠⁠⁠Instagram⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠Twitter⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠LinkedIn⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠Youtube⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠Grow Everything⁠⁠⁠⁠⁠⁠⁠⁠Music by: Nihilore Production by: Amplafy Media
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    1 h y 3 m
  • 176. Dare to Commercialize: Damien Perriman’s eXoZymes Playbook
    Apr 10 2026
    Damien Perriman, Chief Commercial Officer of eXoZymes and the commercial lead behind the NCTx spinout, breaks down why cell-free biomanufacturing changes the rules for scaling nature’s rare molecules. Damien explains why the team spun NCTX out as a separate commercial vehicle, what it means to successfully transfer a process to a partner manufacturer (including a milestone Cayman validation), and why NCT (n-trans-caffeoyl tyramine), a trace compound found in peppercorns and hemp seed husks, has drawn so much attention as the only known agonist of HNF4A, a metabolic “switch” tied to mitochondrial function. The conversation also covers the logic behind launching first in supplements, how to build credibility in a crowded category through safety and product consistency, how regulatory timelines shape strategy, and why industrial biotech needs to move from platform-first stories to molecule-led business cases that match real market demand.Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing?Learn more at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.messaginglab.com/groweverything⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Chapters:(00:00:00) Welcome, introductions, and why tech transfer matters(00:02:10) Why eXoZymes spun out NCTX to commercialize faster(00:03:30) Cayman scale-up milestone: 99% conversion and 99.6% purity(00:05:20) What the Cayman validation proves for product delivery and partners(00:08:10) Why launch NCT in supplements first, and what GRAS enables(00:10:00) Building credibility in supplements: safety, purity, and consistency(00:12:05) What HNF4A is, and why NCT is the only known agonist(00:14:30) What’s next: more human use studies, dose regimens, and GLP-1 adjacencies(00:16:00) NCT vs GLP-1s: “metabolic restoration” and where it might fit(00:18:10) “Natural” vs safe and effective: what really matters(00:21:00) Examples of trace natural molecules scaled for human use(00:22:30) GRAS + FDA timelines: how they’re navigating regulatory reality(00:26:00) The Molecule Manifesto: why industrial biotech needs molecule-led business cases(00:31:00) How eXoZymes chooses what to work on (idea management system)(00:33:00) Vision: what success looks like in 5–10 years(00:35:00) Quickfire: NCT in ice cream, NCT as “WALL-E,” and other rapid takes(00:38:10) What people misunderstand about cell-free biomanufacturing(00:40:00) Wrap-up + post-episode reflectionLinks and Resources:eXoZymesInterview: Cayman Chemical validates eXoZymes' technology and scalabilityeXoZymes’ Cell-Free Biomanufacturing Platform Gets Positive Feedback from Cayman ChemicaleXoZymes on LinkedInDamien Perriman - new CCO129. No Cells? No Problem! eXoZymes' Michael Heltzen on the Future of Microbe-Free Biotech29. Gut Check with Stephanie Culler: Persephone’s Quest for Microbiome Breakthroughs170. There's a Bug for That: Sophia Xu on CarbonBridge's Notebook Bioreactors166. The Great Reformulation: Joshua Lachter Rethinks How We Make Everything at ScaleTopics Covered:cell-free biomanufacturing, industrial biotech, NCTx, HNF4A, metabolic switch, tech transfer, CDMO, supplements vs pharma, GRAS, purity and consistencyHave a question or comment? Message us here:Text or Call (804) 505-5553⁠⁠⁠⁠⁠⁠⁠⁠Instagram⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠Twitter⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠LinkedIn⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠Youtube⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠Grow Everything⁠⁠⁠⁠⁠⁠⁠⁠Music by: Nihilore Production by: Amplafy Media
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    46 m
  • 175. Seaweed Is the New Oil: Mari Granström Builds Origin by Ocean
    Apr 3 2026
    Mari Granstrom, founder and “chief executive activist” of Origin By Ocean, joins the Grow Everything podcast to explain how massive seaweed blooms, driven by nutrient pollution and eutrophication, can become a regenerative feedstock for bio-based and biodegradable chemicals. Mari shares how a career in industrial biochemistry, plus years of scuba diving and growing up near the polluted Baltic Sea, shaped their mission to transform invasive sargassum into high-performance ingredients that can replace many oil-derived inputs in everyday products. The conversation covers the scale of the sargassum problem across the Caribbean and Gulf of Mexico, how Origin By Ocean processes seaweed into “white powders” customers can use in cosmetics and nutraceuticals, and why the future of climate entrepreneurship needs diversity, integrity, and business models that restore ecosystems instead of extracting from them.Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing?Learn more at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.messaginglab.com/groweverything⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Chapters:(00:00:00) Seaweed is the oil we never used(00:01:00) Karl’s Hidden Brain live show story + talking to strangers(00:03:00) Spring break travel + staying plugged into biotech(00:04:05) Pfizer Oscars ad: what “breakthrough” messaging gets right(00:08:15) Echo Biotech + NYC’s biotech network, from biomaterials to investing(00:11:10) Meet Mari Granstrom and Origin By Ocean (how they met at Climate Week)(00:14:00) Mari’s path: biochemical expertise inside big chemical companies(00:16:25) Eutrophication 101 + spotting seaweed blooms as future biomass(00:19:20) The sargassum crisis: 40–60M tons/year in the Caribbean + Gulf(00:21:00) Is this just a Gulf issue? Baltic Sea vs “real oceans”(00:23:00) Turning research into a real biorefinery business(00:25:00) “Chief executive activist”: science, entrepreneurship, advocacy as one role(00:28:05) How seaweed can replace oil-derived functionality in everyday products(00:30:10) Regenerative value chains vs ESG (doing less harm vs net-positive)(00:33:00) Why diversity (backgrounds, not just demographics) drives better solutions(00:34:00) Future-casting: where marine biomass will (and won’t) make sense(00:37:00) Quickfire: ocean’s passive-aggressive text, algae blooms, nudibranchs(00:40:00) Demo products: cosmetics, hair growth, makeup + showing customers potential(00:41:00) Wrap-up reflections (seaweed as feedstock, alternate history)Links and Resources:Mari Granstorm episode linksSynBioBeta Pass - Discount code: Grow Everything Topics Covered:fermentation, biomanufacturing, yeast, Lallemand, enzymes, biofuels, xylose, Saccharomyces cerevisiae, genomics, synthetic biologyHave a question or comment? Message us here:Text or Call (804) 505-5553⁠⁠⁠⁠⁠⁠⁠Instagram⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠Twitter⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠LinkedIn⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠Youtube⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠Grow Everything⁠⁠⁠⁠⁠⁠⁠Music by: Nihilore Production by: Amplafy Media
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    48 m
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