If you want to get leaner and live longer check out https://milliondollarbodylabs.com

How can you leverage positive thinking and simple lifestyle habits to change your biological age by a decade?

In this episode, I talked with Jon Sabes, a longevity researcher and entrepreneur. He has worked with biomarkers of aging and health for the life insurance industry. Jon shares how his mother's passing shaped his book, Healthy Wealthy Longevity. I learned about the connection between positive thinking, physical activity, and gene expression through epigenetics. We discussed the importance of mastering the basics: eating whole foods, consistent movement, connection, and purpose. I also asked Jon how tackling difficult physical challenges builds mental resilience and self-belief.

• Lifestyle is a powerful driver of longevity: Lifestyle habits strongly influence gene expression (epigenetics).

• Reprogramming the subconscious is key to health: Override negative thought narratives by intentionally inputting "brain food" (positive psychology) combined with exercise, which can drive positive gene expression.

• Build mental resilience: Challenging physical activity creates a mental muscle of resiliency, helping overcome negative self-talk and building proof of capability.

• Focus on the basics before biohacking: Prioritize holistic lifestyle—eating whole foods, constant movement, connecting with others, and having purpose—as these cover 80% of health and longevity needs.

• The Blue Zones teach the value of community and purpose: Populations living long, happy lives prioritize strong community and purpose, often without being financially rich.

• Biological age can be measured: Epigenetic biomarkers (DNA methylation patterns derived from a blood test) can reveal a biological age that is older or younger than chronological age. Jon's biological age is about 10 years younger than his chronological age.Healthy & Wealthy Longevity? Ft. Jon Sabes

• Use prompt journaling: A daily practice of prompt journaling helps self-coach, set intentions, and maintain focus on goals, fostering gratitude and daily improvement.

• Website: https://longevityfp.com

• LinkedIn: longevityfp

• Facebook: LongevityFP

• Instagram: @longevity.fp

• Jon Sabes's Book: Healthy Wealthy Longevity

Nate Palmer:

The founder of The Million Dollar Body and author of "The Million Dollar Body Method", Nate has been coaching for over 15 years and has worked personally with over 1,000 clients.

• Website: https://milliondollarbodylabs.com/
  
  

• Book: The Million Dollar Body Method
  
  

• Lean Energy Stack: https://milliondollarbodylabs.com/pages/lean
  
  

• Instagram: @_milliondollarbody

You don't need another diet plan or "perfect" fitness routine — you need curiosity.
In this episode, Nate reveals how running N=1 experiments (small, personal tests) can help you finally break out of copy-paste fitness and start getting results that actually fit your body and lifestyle.

You'll learn how to test what works for you without overcomplicating things — whether that's shifting your meal timing, adjusting your workouts, or simply paying attention to how your body feels.
By the end, you'll know exactly how to stop guessing and start discovering what helps you feel unstoppable.

In this episode, you'll discover:

• Why most fitness "plans" fail and how to reframe them as experiments

• The 3-step framework for testing new habits without tracking everything

• How to evaluate your results like a scientist, not a judge

• Real-world examples of N=1 experiments that improve energy, focus, and fat loss

• Why curiosity, not discipline, is the real secret to consistency

Episode Highlights:
00:00 – Why following every rule still doesn't work
03:20 – The "Copy-Paste Fitness" trap
06:45 – What N=1 means and why it changes everything
09:10 – How to run your own 14-day experiment
13:40 – How to track energy and progress without obsessing
17:15 – Real-life experiments Nate and clients have tested
22:00 – The power of curiosity over willpower
25:00 – Closing: Why you can't fail an experiment

Resources Mentioned:

• 5-Day Sugar Detox – jumpstart your energy and reset cravings

• Complete Restore – magnesium + glycine + taurine for deep sleep and recovery

• The Prime Protocol – the complete system for building muscle, burning fat, and feeling amazing

Follow Nate:
Instagram – @_milliondollarbody
YouTube – Million Dollar Body
Website – www.milliondollarbodylabs.com

If you want to get leaner and live longer check out https://milliondollarbodylabs.com

Why do our bodies slowly break down, even if we eat right and exercise? We dive deep into the biological switch at the cellular level that determines human longevity.

I spoke with Dr. Bill Andrews, the father of telomere biology and a co-discoverer of telomerase. He explained why aging happens: telomeres, the protective caps on our DNA, shorten every time a cell divides, acting like a cellular clock. We talked about an obsession with curing aging. We discussed methods to re-lengthen telomeres, primarily using plant extracts to turn the telomerase gene back on in normal cells, a process currently being researched by his company, Sierra Sciences. We also discussed the biggest myth in anti-aging science and how certain types of exercise can accelerate aging by increasing cell division.

• Telomeres are DNA sequences found at the tips of chromosomes; they function as protective caps (like shoelace aglets) and control gene expression.

• The shortening of telomeres occurs every time a cell divides because the cell lacks the ability to duplicate the entire DNA strand to the very end (analogous to a bricklayer falling off the end of a wall before placing the last brick). This phenomenon represents a hard, fast limitation on our lifespan.

• Telomerase is the enzyme responsible for preventing telomere shortening. Reproductive cells (primordial germ cells) possess this enzyme, which prevents the species from going extinct with ever-shorter telomeres.

• The primary mission of current research is to reactivate the telomerase gene in somatic cells (non-reproductive body cells), where the gene's "dimmer switch" is currently turned off.

• Sierra Sciences focuses 95% of its efforts on screening fractionated nutraceuticals (plant extracts), looking for small molecules that can bind to and dislodge the repressor protein that keeps the telomerase gene turned off.

• Dr. Andrews states that the biggest myth in longevity is the claim that a product reverses aging simply because it reverses a biomarker correlated with aging. He uses the "Betty White Test" to demonstrate that no product currently exists that truly reverses aging.

• Activities that force extensive cell division, such as muscle bodybuilding, microdermabrasion (using acids or lasers on the face), and immune boosters, accelerate telomere shortening and therefore accelerate aging.

• When pursuing endurance exercise (running, biking, kayaking), it should be done consistently and kept fun; too little or too much intensity accelerates aging (a "Goldilocks effect").

• Documentary: The Immortalist https://theimmortalists.com

• Company/Website: Touchstone Essentials https://thegoodinside.com

• Company/Website: Sierra Sciences https://sierrasci.com

• Contact: Bill Andrews' email BAndrews@SierraSci.com

Nate Palmer:

The founder of The Million Dollar Body and author of "The Million Dollar Body Method", Nate has been coaching for over 15 years and has worked personally with over 1,000 clients.

• Website: https://milliondollarbodylabs.com/
  
  

• Book: The Million Dollar Body Method
  
  

• Lean Energy Stack: https://milliondollarbodylabs.com/pages/lean
  
  

• Instagram: @_milliondollarbody