Gaelan Combs: Dexamethasone Pre-treatment Impact | Ep. 109

In this episode of The Dairy Nutrition Blackbelt Podcast, Gaelan Combs, a PhD student at Iowa State University, discusses the impact of dexamethasone pre-treatment on metabolism and productivity during a systemic immune challenge. He examines how inflammation affects productivity and why immune activation involves more than just inflammatory markers. Listen now on all major platforms!

"Inflammation is one of the key responses that happens when the immune system is activated, but it’s not the only factor involved."

Meet the guest: Gaelan Combs is a PhD student in Animal Nutrition at Iowa State University, where his research focuses on immune activation and its metabolic effects in dairy cattle. He earned his Bachelor's degree in Dairy Science from the University of Wisconsin–Madison, where he conducted undergraduate research in dairy nutrition.

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What will you learn:

• (00:00) Highlight
• (01:24) Introduction
• (03:31) Immune activation effects
• (04:06) Inflammation and productivity
• (04:51) Dexamethasone's role explained
• (06:19) LPS challenge model
• (11:19) Inflammation vs immune activation
• (13:24) Closing thoughts

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