Nate Tice and Charles McDonald kick off their Week 1 reactions with thoughts on the Buffalo Bills' dramatic comeback victory over the Baltimore Ravens on Sunday night.

Later, Nate and Charles are LIVE reacting to Week 1 of the NFL season. The duo deep dive into the surprising watchability of the Pittsburgh Steelers vs. New York Jets clash (who saw that coming?), the stunning efficiency and dual-threat dynamism of Justin Fields (numbers don't lie!) and why the Green Bay Packers are already looking like a well-oiled, dangerous machine. Plus, they give a shout-out to the rookie phenoms like Emeka Egbuka, Will Johnson, and Harold Fannin Jr. who are already making their presence felt. On the flip side, they lament the New England Patriots' inexplicable struggle in the rain, the Carolina Panthers' utterly dysfunctional Week 1 operation, and the offensive line woes that plagued both the Miami Dolphins and Houston Texans (seriously, our expectations were low, but…)

(00:25) - The Late Hit: Bills-Ravens instant reaction

(11:45) - 3 Highs of Week 1: Aaron Rodgers, Packers, rookie standouts

(34:50) - 3 Lows of Week 1: Sloppy Patriots, Panthers regress, Dolphins & Texans OL

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Week 1 is finally here, and Nate Tice & Charles McDonald are here to deep dive on the biggest games of the week. Nate and Charles kick things off by getting Lost in the Sauce with their three deep dives of the week, featuring the Houston Texans taking on the Los Angeles Rams, a hoss fight of a matchup with Green Bay Packers vs. Detroit Lions and the Baltimore Ravens taking on the Buffalo Bills on Sunday night.

Later, Nate & Charles reveal their Slop Watch: the New England Patriots vs. Las Vegas Raiders, where two quarterbacks will try to take advantage of sketchy secondary play. Nate & Charles wrap things up with their Locks of the Week, where they make a Week 1 bold prediction they're sure will come true.

(3:20) - Texans @ Rams preview

(18:30) - Lions @ Packers preview

(34:20) - Ravens @ Bills preview

(49:05) - Slop Watch: Raiders @ Patriots

(58:30) - Locks of the Week

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Nate Tice & Matt Harmon join forces for the final prediction show of the year. Nate & Matt give their playoff, wild card and Super Bowl predictions before diving into their picks for MVP, Offensive & Defensive Player of the Year, Rookies of the Year, the brand-new Protector of the Year award and more. Don't miss this jam-packed episode as Nate & Matt get you ready for the 2025 NFL season.

(4:05) - Season predictions: playoff teams & Super Bowl picks

(25:25) - MVP picks

(33:45) - OPOY & DPOY picks

(49:50) - Rookie of the Year picks

(1:02:45) - Protector of the Year picks

Subscribe to Football 301 on your favorite podcast app:

🎧 Apple Podcasts

🎧 Spotify

🖥️ YouTube

📢 Check out the Yahoo Sports podcast network or yahoosports.tv