Ep 287: Spermidine: The Secret Fertility Booster Hiding in Your Kitchen

Join Dr. Carrie Bedient from the Fertility Center of Las Vegas, Dr. Susan Hudson from Texas Fertility Center, and Dr. Abby Eblen from Nashville Fertility Center for another fascinating episode of Fertility Docs Uncensored. This week, we’re joined by Leslie Kenny, a researcher who is part of the Oxford Longevity Project and Oxford Healthspan. She shares her groundbreaking research on spermidine—a natural compound made from L-Arginine and found in foods like mushrooms, peas, beans, and legumes. Leslie explains how spermidine promotes autophagy (cell renewal), improves mitochondrial health, reduces inflammation, and lowers oxidative stress, all of which are important for egg and sperm quality. She also highlights the role of gut health in producing spermidine and how fasting can boost natural levels. Leslie discusses how spermidine enhances sperm function, including its role in the acrosomal reaction, and notes it’s even present in breast milk. Oxford Healthspan has developed a supplement called Primeadine that may benefit both men and women undergoing fertility treatments. She recommends at least 1 mg of spermidine daily, with studies showing improvements after just 30 days of use.This podcast was sponsored by Reproductive Science Center of the Bay Area. Use code FERTILITYDOCS on the Primeadine website for an extra discount!