Ep 25 GLP-1 Basics: The Hormone Fueling the Hype

In this kickoff episode, we break down GLP-1 in simple terms: Your body's natural "hunger brake," how it works in the gut, brain, and heart, why it sometimes falters, and a quick look at the drugs mimicking it. No jargon overload—just the essentials to get you curious. (Based on my research, women's real stories, and science-backed sources—always chat with your doctor.)

Key Takeaways:

• GLP-1 is like a signal flare from your gut after eating, helping control hunger and blood sugar.
• It travels to your brain (thermostat for cravings) and even protects your heart.
• When production dips (due to stress or diet), drugs like Ozempic step in as boosters—but they're tools, not magic.
• Teaser: We'll unpack hype, risks, and real journeys in episodes ahead.

Weekly Challenge: Hunger Check—Pause before meals: True hunger or something else? Share your insights at @undieting101!

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Resources & Science Behind the Episode:

1. Holst, J. J. (2007). The physiology of glucagon-like peptide 1. Physiological Reviews. Link to PubMed – GLP-1 basics and gut functions.
2. Baggio, L. L., & Drucker, D. J. (2007). Biology of incretins: GLP-1 and GIP. Gastroenterology. Link to PubMed – How GLP-1 slows digestion.
3. Turton, M. D., et al. (1996). A role for glucagon-like peptide-1 in the central regulation of eating. Nature. Link to PubMed – Brain's hunger control.
4. Marso, S. P., et al. (2016). Liraglutide and Cardiovascular Outcomes (LEADER Trial). New England Journal of Medicine. Full Article – Heart benefits.
5. Wilding, J. P. H., et al. (2021). Once-weekly semaglutide (STEP 1 Trial). New England Journal of Medicine. Full Article – Agonist efficacy and use.

Disclaimer:

The insights and tips shared in this podcast are based on my personal journey and are for informational and motivational purposes only. They are not intended as a substitute for professional medical advice. If you have specific health concerns or questions related to your medical condition, please consult with your healthcare provider. Remember, your health journey is unique, and what has worked for me might not be suitable for everyone. The content here does not aim to diagnose, treat, cure, or prevent any disease, and results from following the strategies discussed can vary.