Ep. 185 How to Make a Drug Pt 2: Libraries and Design

On this second episode about drug discovery, we discuss small molecule drug libraries and the challenges behind rational design! Don't know what that means? Tune in to find out!

References:

https://www.frontiersin.org/articles/10.3389/fcell.2019.00107/full

https://next.cancer.gov/discoveryresources/resources_ndl.htm

https://www.molbiolcell.org/doi/10.1091/mbc.E22-08-0377

https://www.fda.gov/news-events/press-announcements/fda-approves-first-gene-therapy-treatment-certain-patients-duchenne-muscular-dystrophy

https://www.goodrx.com/health-topic/gene-therapy/crispr-therapeutics-vertex-exa-cel

https://www.broadinstitute.org/what-broad/areas-focus/project-spotlight/crispr-timeline