[EP.17]Mastering Your Genetic Code for Optimal Health: Dr. Bob Miller’s Latest Insights

Dr. Joel Rosen:I would like to welcome Bayou Ck. I believe this is our third interview with Bob. Yeah, he is a traditional naturopath specializing in the field of genetics-specific nutrition. Bob is also an educator. He lectures nationally and internationally at seminars to educate health practitioners about genetic variants and nutritional supplementation for obtaining optimal health. Bob is also a researcher. He’s expanding his genetic research efforts. He founded and personally funded the NutriGenetic Research Institute to study the relationship between genetic variants and presenting symptoms. He’s also a nutritional supplement formulator and a genetic analysis software creator. Bob here is going to help us learn about cracking the code. So, Bob, welcome once again to another edition of helping people get their health back. Dr. Bob Miller:Oh, it was a pleasure to be with you. It’s um, I always enjoy these interviews because we’ve, we always have a good time, we kind of geek out a little bit on some of the deep dives on biochemistry, and it was a lot of fun. So yeah, do the same thing today. Dr. Joel Rosen:Excellent. So okay, so Bob, go ahead and share your screen and give our listeners what’s the latest and greatest, in what you’re researching. Dr. Bob Miller:Already? Well, our subject today is going to be superoxide. Now, you know, the traditional naturopathic philosophy has always been that most problems we see come from inflammation, from excess free radicals. We’ve been on that path for all of our time working: what is creating extra free radicals, and then what is causing us to not be able to break those free radicals down. Now, on the other hand, free radicals are bad if they’re in excess, but they can be our friend. One of my favorite sayings has been, you know, they can be your friend unless they’re not. So we need free radicals to kill viruses and bacteria. And even if we have bad cells inside the body, we need inflammation to kill them. But on the other hand, if it goes to the extreme, that’s when we have a problem. So we tend to villainize free radicals, and rightfully so. But on the other hand, we have to be careful that we don’t eradicate all free radicals, that they do play a role for us. Our subject again is superoxide. And again, we always mention that we’re not treating any disease here. This is for educational purposes only and informational. So our learning objectives today are what superoxides, and random superoxide, and then we’re going to delve into how excess superoxide impacts. We’re going to look at pathways of how we make superoxide and pathways of how we reduce it. And then we’re going to dig into something called ferroptosis, where superoxide causes iron to do some really bad things. So, you’ll see here it’s all about balance. Superoxide plays a role in the body at times, but in excess, it can cause all kinds of problems for us. Now, this little chart here that you see. You’ll see on the left there it says oxygen o2 and unfortunately, that too got knocked off. But as you know, oxygen is o2. So what you’re seeing and by the way, do you see my little love? Okay, good. So the oxygen is two oxygen atoms, and you see these two little dots there. That’s electrons. So we all remember even from high school that, you know, you’ve got the neutron-proton and the electron, and they need to be paired. So here’s two together, here’s two together, here’s two together, they’re all paired up. This superoxide occurs when an extra electron comes on here that shouldn’t be there, and that makes it very unstable. And I’m going to show you in a little bit why this can be the root cause of a lot of our problems. Now, the body is pretty amazing. There are multiple ways here, but I’m going to show you one of the main ways. There’s an enzyme called superoxide dismutase. Number two, so this is superoxide. Dismutase means to break it down. And it takes the mineral manganese, not magnesium, manganese. And I’ll show you a better chart later, but it turns it into oxygen. But it also turns it into hydrogen peroxide. And hydrogen peroxide again, is not all bad. Sometimes we use hydrogen peroxide to kill pathogens. But if we have too much of it and we have dysregulated iron, we’ll make what are called hydroxyl radicals that damage the DNA and just wreak havoc throughout the body. However, we do have other mechanisms. If we have enough catalase, that’ll turn that hydrogen peroxide into water and oxygen. And there’s something called glutathione that we’ll dig into a little bit later. And there’s an enzyme called glutathione peroxidase that takes that glutathione and turns it into two water molecules. So there’s a lot that can go wrong here; we can overproduce superoxide. We’re going to show you how you can have less than optimal production, less than optimal catalase glutathione, where you can have iron dysregulation. So this is a ...