E15: Singular Genomics | ATAC-seq

Sharing a flowcell, reinvented

Chapters:

- 00:00 usegalaxy.org

- 07:55 Singular Genomics start

- 21:55 Max Reads

- 29:40 DNA Structure / ATAC-seq

Setup galaxy on local hardware:

https://galaxyproject.org/admin/get-galaxy/

G4 is competing with Illumina:

https://www.genengnews.com/topics/omics/fast-and-flexible-singulars-g4-takes-aim-at-illuminas-sequencing-superiority/

Singulars chemistry is one of many:

https://www.nature.com/articles/d41586-023-00512-4

How max reads works:

https://techwriting.singulargenomics.com/max-read/Max-Read-Kit-User-Guide-600026.pdf

Small intro to DNA Structures:

https://en.wikipedia.org/wiki/Nucleic_acid_quaternary_structure

Intro to ATAC-seq:

https://www.nature.com/articles/s41596-022-00692-9

PS:

As of 2025, Singular does not advertise DNA/RNA Sequencing on their G4 anymore, but shifted to spatial data, including their G4X: https://www.singulargenomics.com/

Since 2018, West German Genome Center (⁠https://wggc.de/⁠) operates as the next generation sequencing facility and supports research in genomics & transcriptomics by providing expertise and sequencing services. WGGC is a part of the Next Generation Sequencing Competence Network (NGS-CN: ⁠https://ngs-kn.de/⁠) – network of NGS core facilities in Germany. Listen to our podcast and we're happy to receive your feedback&questions via Email (podcast[dot]explain[at]gmail[dot]com ).

License Notice

This podcast including all episodes, unless otherwise noted, is licensed under a ⁠⁠⁠⁠⁠Creative Commons Attribution 4.0 International License⁠⁠⁠⁠⁠.You are free to share, remix, and use this content as long as you give appropriate credit, provide a link to the license, and indicate if changes were made.

Attribution:

Podcast Title: Explain Podcast

Creators: Iuliia Novoselova, Daniel Rickert

Website: ⁠⁠⁠⁠⁠https://ngs-cn.de/explain-podcast/⁠