E13: Sequencing by Avidity | Element Biosciences + XLEAP

Because sometimes a jellyfish prevents quenching

Chapters:

01:00 - XLeap update from Illumina

08:00 - Avidites start, splitting the problems

13:20 - In-depth comparison to Illumina

22:00 - Element summary

23:30 - Bioinformatics tools: Jellyfish, KAT

25:00 - QuickGen: GWAS

Illumina about their XLeap: https://www.illumina.com/science/genomics-research/articles/data-quality-q-scores.html

Sandiegomics about element: https://sandiegomics.com/element-beats-illumina-to-the-200-genome/

Nature paper about the chemistry: https://www.nature.com/articles/s41587-023-01750-7

Jellyfish for k-mer counting: https://github.com/gmarcais/Jellyfish

GWAS Catalog: very nice data collection: https://www.ebi.ac.uk/gwas/diagram

Correcting population-based GWAS bias: https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1011242

Since 2018, West German Genome Center (https://wggc.de/) operates as the next generation sequencing facility and supports research in genomics & transcriptomics by providing expertise and sequencing services. WGGC is a part of the Next Generation Sequencing Competence Network (NGS-CN: https://ngs-kn.de/) - network of NGS core facilities in Germany. Listen to our podcast and we're happy to receive your feedback&questions via Email (podcast[dot]explain[at]gmail[dot]com ).

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This podcast including all episodes, unless otherwise noted, is licensed under a ⁠⁠⁠⁠Creative Commons Attribution 4.0 International License⁠⁠⁠⁠.You are free to share, remix, and use this content as long as you give appropriate credit, provide a link to the license, and indicate if changes were made.

Attribution:

Podcast Title: Explain Podcast

Creators: Iuliia Novoselova, Daniel Rickert

Website: ⁠⁠⁠⁠https://ngs-cn.de/explain-podcast/⁠