Dr. M's Women and Children First Podcast Podcast Por Dr. Chris Magryta "Dr. M" arte de portada

Dr. M's Women and Children First Podcast

Dr. M's Women and Children First Podcast

De: Dr. Chris Magryta "Dr. M"
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Providing listeners with cutting edge science based information for maternal and child health©Copyright 2021 Krzysz Media LLC Enfermedades Físicas Higiene y Vida Saludable
Episodios
  • Dr. M’s SPA Newsletter Volume 15 Issue 19

    Dr. M’s SPA Newsletter Volume 15 Issue 19
    Sep 26 2025
    For parents of special needs children, I honor you today. I witness your strength every day in clinic. You rise to meet challenges that many cannot begin to imagine, truly. You navigate medical appointments, therapy sessions, school meetings, and the unpredictable rhythms that come with raising a child with special needs. Often without pause, without adequate rest, and without the recognition you deserve. For those single parents carrying this day to day reality, a double level of gratitude for you. I want to pause for a moment and say what is too rarely said: you are extraordinary. Truly extraordinary. Your love is not passive, it is an active force. It shows up at 2 AM when a child can’t sleep, in the quiet patience during a meltdown, in the persistence to advocate for services in a dysfunctional system requiring resilience summoned when the system says “no” but you know your child needs a “yes.”.... and a discussion of nutritional dark matter. Enjoy, Dr. M
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    Menos de 1 minuto
  • Dr. M’s Women and Children First Podcast #97 Paul Offit, MD – Vaccines – What Do We Know in 2025 Part 2?

    Dr. M’s Women and Children First Podcast #97 Paul Offit, MD – Vaccines – What Do We Know in 2025 Part 2?
    Sep 21 2025
    Welcome back to Dr. M’s Women & Children First, where we explore the front lines of children’s health and what matters most for our families. Today I’m honored to bring you Dr. Paul A. Offit, the Director of the Vaccine Education Center and Professor of Pediatrics in the Division of Infectious Diseases at Children’s Hospital of Philadelphia. He also holds the Maurice R. Hilleman Professorship of Vaccinology at the University of Pennsylvania. Dr. Offit is a globally recognized expert in virology and immunology. He has served on the CDC’s Advisory Committee on Immunization Practices and FDA’s Vaccines and Related Biological Products Advisory Committee. He’s co-editor of the seminal vaccine textbook Vaccines, and for decades has been one of the clearest scientific voices defending evidence, transparency, and children’s health. This week, we’ll dig into COVID, vaccine policy, and what’s ahead for children in light of the latest shifts. Among current headlines: Healthy children and pregnant women are no longer being uniformly recommended for COVID vaccines by Health Secretary Robert F. Kennedy Jr., a decision that’s stirring debate among pediatricians and public health experts like Dr. Offit. He’s sharply voiced concerns about removing key vaccine recommendations without new data, and about the broader implications of loosening vaccine guidance for the public good. In this conversation, we’ll cover: What the science says now about bivalent COVID vaccines in kids How recent policy changes affect vaccine access, trust, and safety What parents need to know—what’s changed, what’s stable, and what remains uncertain This is my third time talking with Dr. Offit, and as always, I expect you’ll leave with clarity, evidence, and questions worth sharing. I hope you enjoy this conversation. Let’s dive in. Dr. M
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    45 m
  • Dr. M’s SPA Newsletter Volume 15 Issue 18

    Dr. M’s SPA Newsletter Volume 15 Issue 18
    Sep 13 2025
    Breastmilk is Dynamic Cellular and transcriptional diversity over the course of human lactation This recent 2022 paper in the Proceedings of the National Academy of Sciences by Dr. Nyqiust and colleagues is a site for sore eyes. It offers a remarkable, high-resolution portrait of how the cellular landscape of human breast milk (hBM) shifts over time. The authors capture something both scientifically rich and uniquely human: the dynamic, living composition of milk as it adapts to the changing needs of mother and child. The abstract: "Human breast milk is a dynamic fluid that contains millions of cells, but their identities and phenotypic properties are poorly understood. We generated and analyzed single-cell RNA-sequencing (scRNA-seq) data to characterize the transcriptomes of cells from hBM across lactational time from 3 to 632 d postpartum in 15 donors. We found that the majority of cells in hBM are lactocytes, a specialized epithelial subset, and that cell-type frequencies shift over the course of lactation, yielding greater epithelial diversity at later points. Analysis of lactocytes reveals a continuum of cell states characterized by transcriptional changes in hormone-, growth factor-, and milk production-related pathways. Generalized additive models suggest that one subcluster, LC1 epithelial cells, increases as a function of time postpartum, daycare attendance, and the use of hormonal birth control. We identify several subclusters of macrophages in hBM that are enriched for tolerogenic functions, possibly playing a role in protecting the mammary gland during lactation. Our description of the cellular components of breast milk, their association with maternal–infant dyad metadata, and our quantification of alterations at the gene and pathway levels provide a detailed longitudinal picture of hBM cells across lactational time. This work paves the way for future investigations of how a potential division of cellular labor and differential hormone regulation might be leveraged therapeutically to support healthy lactation and potentially aid in milk production." (Nyquist et. al. 2022) And more information on breastmilk immunology and a recipe. Dr. M
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    13 m
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