Dementia in Diabetes - Reasons for Hope or Concern?

In this episode, Prof. Gill Livingston (University College London) and Prof. Thomas van Sloten (UMC Utrecht) explore the complex relationship between diabetes and dementia. People with diabetes face a higher risk of cognitive decline, particularly those with type 2 diabetes, and as treatment improves and life expectancy increases, dementia is becoming a growing clinical challenge. The discussion examines how diabetes medications, including GLP-1 receptor agonists and SGLT2 inhibitors, may influence cognitive outcomes, the role of lifestyle and vascular risk factors, and why prevention must become central to diabetes care. This episode also highlights the urgent need for clinical trials that include dementia and cognition as primary outcomes.