Bret Weinstein speaks with Dr. Mark Cannon on the subject of the microbiome.

Dr. Mark L Cannon is a Professor Emeritus from Ann & Robert H. Lurie Children's Hospital of Chicago and Northwestern University.

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Theme Music: Thank you to Martin Molin of Wintergatan for providing us the rights to use their excellent music.

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Bret Weinstein on confronting the new threat to free speech.

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Today we give a tribute to Charlie Kirk: who he was, how he engaged with people, and what we lost when we lost him. Kirk was a patriot, a Christian, a husband and a father, and believed in the humanity of all people. Then, for the living: regenerative agriculture, Polyface Farm, and the rejection of Big Ag in favor of real food and community.

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Join us on Locals! Get access to our Discord server, exclusive live streams, live chats for all streams, and early access to many podcasts: https://darkhorse.locals.com/

Heather’s newsletter, Natural Selections (subscribe to get free weekly essays in your inbox): https://naturalselections.substack.com

Our book, A Hunter-Gatherer’s Guide to the 21st Century, is available everywhere books are sold, including from Amazon: https://amzn.to/3AGANGg (commission earned)

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Mentioned in this episode:

Robert Malone on the plot to get RFK Jr: https://www.malone.news/p/the-plot-to-get-rfk

Brownstone Institute and Spirits of America: https://brownstone.org/books/

Polyface Farm: https://polyfacefarms.com

Back to the Land: https://naturalselections.substack.com/p/back-to-the-land

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Today we discuss MAHA, vaccines, Covid, autism, and ostriches. Senator Ron Johnson held a hearing on the corruption of science, at which Jake Scott (MD), Toby Rogers (PhD), and lawyer Aaron Siri testified about vaccine safety testing and the relationship between vaccines and autism. The new MAHA Strategy report attributes poor diet, aggregation of environmental chemicals, lack of physical activity, chronic stress, and overmedicalization to the decline in children’s health. Meanwhile, people who have been fooled by the fear campaign celebrate getting their newest Covid boosters. And in Canada, ostriches are at risk of being killed because of a misunderstanding of immunity, but people are fighting back. The immune system that defends the body politic is discovering how to defeat the infection. The battle is over the public consciousness.

While we were livestreaming, news broke that Charlie Kirk was shot during an event in Utah and sadly passed away shortly after.

“Charlie Kirk was a beautiful person. He died engaging his foes honorably. I truly hope he’s right about the universe and is receiving his reward. I’m beyond heartbroken for his lovely family—we must take care of them. Let’s live up to his example.” – Bret Weinstein

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Join us on Locals! Get access to our Discord server, exclusive live streams, live chats for all streams, and early access to many podcasts: https://darkhorse.locals.com

Heather’s newsletter, Natural Selections (subscribe to get free weekly essays in your inbox): https://naturalselections.substack.com

Our book, A Hunter-Gatherer’s Guide to the 21st Century, is available everywhere books are sold, including from Amazon: https://amzn.to/3AGANGg (commission earned)

Check out our store! Epic tabby, digital book burning, saddle up the dire wolves, and more: https://darkhorsestore.org

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Mentioned in this episode:

Congressional hearing: https://www.hsgac.senate.gov/subcommittees/investigations/hearings/how-the-corruption-of-science-has-impacted-public-perception-and-policies-regarding-vaccines/

Childhood vaccines aren’t tested against placebo: https://naturalselections.substack.com/p/childhood-vaccines-arent-tested-against

MAHA Strategy report: https://www.whitehouse.gov/wp-content/uploads/2025/05/MAHA-Report-The-White-House.pdf

Covid boosters to show RFK: https://x.com/newstart_2024/status/1964562477716558123

Universal Ostrich Farm at Rebel News: https://www.rebelnews.com/breaking_b_c_ostriches_temporarily_saved_from_cfia_cull_by_interim_stay_order

Ostriches - Politico: https://www.politico.com/news/2025/07/15/why-rfk-jr-wants-canada-to-pardon-400-ostriches-00455360

Ostriches - Wall Street Journal: https://www.wsj.com/world/americas/universal-ostrich-farm-canada-jfk-oz-f6548a6a

Ostriches - WaPo: https://www.washingtonpost.com/world/2025/08/22/ostrich-bird-flu-canada-cull-rfk/

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Today we discuss RFK Jr. the CDC, autism and trans activism. Kennedy revealed this week that in 2002, the CDC destroyed data that showed that children who got the MMR vaccine before 36 months of age had far higher rates of autism than did those who get the vaccine later in life. An HHS report will soon be released that ties Tylenol use during pregnancy to autism—what does this tell us about past public health advice, safety and risk? How can we all become better at pattern recognition? Florida Surgeon General Joe Ladapo is moving away from vaccine mandates for all citizens, while the governors of the three West coast states are conflating “science” with “ideology” while pining for a Covid-era-style CDC. In trans land: comedy writer Graham Linehan was arrested for saying mean things on-line, while trans-activists are not arrested when they threaten to kick and punch those who don’t believe that men can become women. We explore the mental illness of trans-deluded people, and discuss Vivian Wilson, Elon Musk’s oldest son, who thinks he’s a girl.

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Join us on Locals! Get access to our Discord server, exclusive live streams, live chats for all streams, and early access to many podcasts: https://darkhorse.locals.com

Heather’s newsletter, Natural Selections (subscribe to get free weekly essays in your inbox): https://naturalselections.substack.com

Our book, A Hunter-Gatherer’s Guide to the 21st Century, is available everywhere books are sold, including from Amazon: https://amzn.to/3AGANGg (commission earned)

Check out our store! Epic tabby, digital book burning, saddle up the dire wolves, and more: https://darkhorsestore.org

(Thumbnail Andrew Harnik/Getty Images)

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Mentioned in this episode:

RFK before Congress: https://x.com/wallstreetapes/status/1964154838830502080

WSJ on Tylenol in pregnancy: https://www.wsj.com/health/healthcare/rfk-jr-hhs-to-link-autism-to-tylenol-use-in-pregnancy-and-folate-deficiencies-e3acbb4c

Western Health Alliance: https://apps.oregon.gov/oregon-newsroom/OR/GOV/Posts/Post/oregon-washington-and-california-form-western-health-alliance

Doyle on Linehan arrest in UnHerd: https://unherd.com/2025/09/the-shameful-arrest-of-graham-linehan/

Punch TERFs: https://x.com/babybeginner/status/1963504508509593772

Good genetics: https://x.com/hazelappleyard_/status/1963315154277593109

Vivian Wilson in NY Mag: https://www.thecut.com/article/vivian-wilson-elon-musk-daughter-2025-fall-fashion-issue-cover-story.html

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Today we discuss the dust-up at the CDC, in which RFK Jr. fires the new director, after which other CDC officials resign, and eight former directors of the CDC pen a letter to the New York Times (as does Bernie Sanders) arguing that Kennedy is a hazard to our health. This follows a reveal from months ago that industry was collaborating to get rid of Kennedy. Also: What does Trump now think of Operation Warp Speed? How has industrialization affected our health? How are the words “vaccine” and “terrorist” being used in Orwellian ways? Is Kennedy a secret eugenicist, or is he—in fact—exactly the opposite? Finally: a new article on the harms and hazards of both SARS-CoV2 and the mRNA biologics said to counter the virus.

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Sundries Farm: Extraordinary hand grown and harvested garlic from a family farm on the volcanic soils of Idaho. Go to http://www.sundriesfarm.com & enter code DarkHorse for 10% off.

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Join us on Locals! Get access to our Discord server, exclusive live streams, live chats for all streams, and early access to many podcasts: https://darkhorse.locals.com

Heather’s newsletter, Natural Selections (subscribe to get free weekly essays in your inbox): https://naturalselections.substack.com

Our book, A Hunter-Gatherer’s Guide to the 21st Century, is available everywhere books are sold, including from Amazon: https://amzn.to/3AGANGg (commission earned)

Check out our store! Epic tabby, digital book burning, saddle up the dire wolves, and more: https://darkhorsestore.org

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Mentioned in this episode:
James Lyons-Weiler, on the plot to get RFK, Jr.: https://www.malone.news/p/the-plot-to-get-rfk
NYT op-ed #1 from Bernie Sanders: Kennedy Must Resign: https://www.nytimes.com/2025/08/30/opinion/bernie-sanders-robert-f-kennedy-jr-resign-hhs.html
NYT op-ed #2 from former CDC directors: We Ran the C.D.C.: Kennedy Is Endangering Every American’s Health: https://www.nytimes.com/2025/09/01/opinion/cdc-leaders-kennedy.html
EvoLens #132: https://www.youtube.com/watch?v=usP2D_qGUZs

CDC didn’t monitor VAERS for COVID safety signals (June 2022): https://childrenshealthdefense.org/defender/cdc-vaers-covid-vaccine-safety/
Psaki interview with Daskalakis: https://x.com/cathy2nottoday/status/1961242623944835538

Daskalakis resignation letter from CDC: https://x.com/dr_demetre/status/1960843433473376602
Zywiec et al 2025. COVID-19 Injections: Harms and Damages, a Non-Exhaustive Conclusion. Journal of American Physicians and Surgeons, 30(3): https://jpands.org/vol30no3/zywiec.pdf

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Today we discuss childhood, fitness, and self-defense; the through-line is freedom. First up: Illinois has become the first state in the Union to mandate mental health screening for children in grades 3 – 12, so that conditions from trauma to anxiety can be detected early. How mandatory will these screenings be? How confidential? What is anxiety, and why are children better off learning to experience and solve their own anxiety, than to be coddled at every turn? We argue that anxiety—like pain, and sadness—are signals from your brain and body that should be listened to rather than erased. Also: childhood is a time of exploration, of mixing reality with fantasy, and should not be a time when adults’ fantasies are imposed on children. Then: the New York Times cannot abide that anything that RFK Jr. does or says makes sense. Finally: do people have the right to defend themselves inside their own homes? Have we forgotten habeas corpus? Are the foundations of democracy coming apart at the seams?

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Branch Basics: Get 15% off Branch Basics with the code DARKHORSE at https://branchbasics.com/darkhorse #branchbasicspod

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CrowdHealth: Pay for healthcare with crowdfunding instead of insurance. It’s way better. Use code DarkHorse at http://JoinCrowdHealth.com to get 1st 3 months for $99/month.

*****

Join us on Locals! Get access to our Discord server, exclusive live streams, live chats for all streams, and early access to many podcasts: https://darkhorse.locals.com

Heather’s newsletter, Natural Selections (subscribe to get free weekly essays in your inbox): https://naturalselections.substack.com

Our book, A Hunter-Gatherer’s Guide to the 21st Century, is available everywhere books are sold, including from Amazon: https://amzn.to/3AGANGg (commission earned)

Check out our store! Epic tabby, digital book burning, saddle up the dire wolves, and more: https://darkhorsestore.org

*****

Mentioned in this episode:

Governor Pritzker signs bill mandating mental health checks for schoolkids: https://news.wttw.com/2025/07/31/pritzker-signs-legislation-implement-universal-mental-health-screenings-illinois-schools

Illinois Bill 1560: https://trackbill.com/bill/illinois-senate-bill-1560-mental-hlth-kids-beacon/2645551/

NYT on the fitness challenge of Kennedy and Hegseth: https://www.nytimes.com/2025/08/25/style/hegseth-rfk-jr-fitness-challenge.html

Breaking and entering report from the Kawartha Lakes Police Service: https://kawarthalakespolice.com/media-releases/media-release-august-18-2025-break-and-enter-assault

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Bret Weinstein speaks with Forrest Maready on the subject of the dual nature of AI, discussing both its potential benefits and risks, particularly in relation to human suffering, dependency, and the evolving concept of truth.

Find Forrest Maready on X at http://x.com/forrestmaready and his website http://forrestmaready.com.

*****

Sponsors:

Everyday Dose: Coffee plus collagen, mushrooms & nootropics – delicious! Get 45% off your first subscription order and also receive free gifts at http://everydaydose.com/darkhorse.

Manukora: the most flavorful, delicious, and nutritious honey you’ll ever have. Get $25 off your starter kit at http://www.Manukora.com/DarkHorse

*****

Join DarkHorse on Locals! Get access to our Discord server, exclusive live streams, live chats for all streams, and early access to many podcasts: https://darkhorse.locals.com

Check out the DHP store! Epic tabby, digital book burning, saddle up the dire wolves, and more: https://www.darkhorsestore.org

Theme Music: Thank you to Martin Molin of Wintergatan for providing us the rights to use their excellent music.

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Mentioned in this episode (Amazon links earn a commission):

The Moth in the Iron Lung: A Biography of Polio https://amzn.to/45CHqGn

The Germ In The Dairy Pail https://amzn.to/4lN2Q8r

The Reason We Kiss https://amzn.to/4g4qegA

A Hunter-Gatherer's Guide to the 21st Century https://amzn.to/45XrayJ

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Timestamps:

00:00:00 Exploring AI Perspectives with author Forrest Maready
00:23:29 The Role of Scarcity in the Human Experience
00:37:03 The Role of Pain and Pleasure in Human Experience
00:48:22 Delayed Gratification and Technology
00:58:47 Truth in the AI Era
01:11:34 The Impact of AI on Creative Work
01:26:35 The Future of Work
01:37:13 The Inevitable Collapse of Complexity
01:48:01 Solution: Build a Wise AI

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