Could the Last of Us Really Happen with Dr. Felipe Santiago-Tirado

In this episode of Rust Belt Science, we delve into the eerie and thought-provoking world of "The Last of Us," exploring whether the events depicted in this popular video game and TV series could transition from fiction to reality. Joining us is Dr. Felipe Santiago-Tirado, an expert in fungal pathogens and Assistant Professor of Biological Sciences at the University of Notre Dame.

Dr. Santiago-Tirado breaks down the science behind the game’s central premise: a fungal infection that turns humans into zombie-like creatures. We discuss the real-life Cordyceps fungus, known for its ability to control the behavior of insects and assess its potential threat to humans. Dr. Santiago-Tirado provides insight into the behavior of fungal pathogens, their evolution, and how environmental changes could possibly expand their host range.

Additionally, we examine the role of climate change, human encroachment on natural habitats, and global connectivity in potentially facilitating such a scenario. Dr. Santiago-Tirado also addresses the biological feasibility of the mutations depicted in the series and discusses current research on fungal diseases.

This episode is not just a fascinating journey into a hypothetical apocalypse but also a crucial look at the real-world implications of scientific research, environmental degradation, and our understanding of the delicate balance between humans and pathogens. Whether you're a fan of "The Last of Us" or a science enthusiast, this discussion will provide you with plenty of food for thought on the resilience of nature and the limits of human control. Tune in to Rust Belt Science for an episode that's as educational as it is thrilling!