Carbamazepine

• Trade: Tegretol
• Class: Anticonvulsant
• MOA: Binds preferably to voltage gated Sodium channels in their inactive conformation, which prevents repetitive and sustained firing of an action potential.
• Indications: Partial and generalized tonic – clonic seizures
• Contraindications: AV Block, bundle branch block, agranulocytosis, bone marrow supression, monoamine oxidase inhibitor therapy
• Side effects: Dizziness, drowsiness, ataxia, N/V, blurred vision, confusion, headache, transient diplopia, visual hallucinations, life threatening rashes.
• Dosing:

Adult:

200mg PO

Pediatric:

6-12 years old: 100mg PO

Less then 6: 10mg/kg PO