Listen in as Nancy Reau, MD, reviews key highlights of the most impactful primary biliary cholangitis (PBC) research and gain insights on how to apply these new advances to clinical practice.

Topics covered include:

• Treatment Goals
• Long-term Data With PPAR Agonists
• Investigational Therapies for Pruritus

Presenter:

Nancy Reau, MD
Professor of Medicine
Richard B. Capps Chair of Hepatology
Chief, Section of Hepatology
Associate Director, Solid Organ Transplantation
Rush University Medical Center
Chicago, Illinois

To download the accompanying slides, visit the program page for this episode:
https://bit.ly/4b2d6YD

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Listen in as Jay H. Shubrook, DO, FACOFP, FAAFP, and Chrisopher Weber, MD, FAAP, FACP, CSCS, daBOM, FOMA, discuss the latest advances in caring for patients with overweight or obesity in the primary care setting, including:

• The Lancet Commission’s new obesity definitions and diagnostic criteria
• Key data on incretin-based antiobesity medications like semaglutide and tirzepatide
• Best practices for patient discussions
• Strategies for incorporating new evidence in your primary care practice

Presenters
Jay H. Shubrook, DO, FACOFP, FAAFP
Professor and Diabetologist
Department of Clinical Sciences and Community Health
Touro University California College of Osteopathic Medicine
Vallejo, California

Christopher Weber, MD, FAAP, FACP, CSCS, daBOM, FOMA
Bariatric Services Medical Director, Ascension Wisconsin
Obesity Medicine Director, Ascension Columbia St Mary’s Bariatric Center
Trustee, Obesity Medicine Association
Adjunct Assistant Professor of Pediatrics
Medical College of Wisconsin
Milwaukee, Wisconsin

Link to full program:
https://bit.ly/4rG7QQp

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Historically, key symptoms of primary biliary cholangitis (PBC), such as pruritus and fatigue, have been understudied and undertreated. Listen now to learn how symptom management should be considered independently of PBC management, and how new therapeutic agents can help.

Topics covered include:

• Mechanisms of pruritus and fatigue in PBC
• Nonpharmacologic treatment options
• An overview of clinical trial data supporting second-line agents for symptom management:
• Bezafibrate
• Elafibranor
• Seladelpar
• Investigational agents:
• Volixibat
• Linerixibat
• Setanaxib

This episode is the third of 3 recap podcasts, featuring audio from our live satellite symposium, Raising the Bar: Innovations in PBC Care. For the full on-demand webcast of this satellite symposium, and to download the accompanying slides, visit the program page for this episode:
https://bit.ly/44ZJ5os

Presenters:
Christopher L. Bowlus, MD
Lena Valente Professor and Chief
Division of Gastroenterology and Hepatology
School of Medicine
University of California Davis
Sacramento, California

Aparna Goel, MD
Clinical Associate Professor of Medicine
Division of Gastroenterology and Hepatology
Stanford University
Palo Alto, California

Aliya F. Gulamhusein, MD,
MPH, FRCPC
Professorship in PSC Research
Clinician Investigator, Toronto General Hospital
Assistant Professor, University of Toronto
Division of Gastroenterology and Hepatology
University Health Network
Toronto, Canada

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