Breakthrough in Gene Therapy: Dr Tom Massey on the Fight Against Huntington's

In a remarkable conversation, clinical neurologist and researcher Dr Tom Massey takes us inside the world of Huntington's Disease (HD) research, sharing the latest breakthroughs that have brought the scientific community closer than ever to a cure.

Just weeks after this interview was recorded, news broke that clinical trials Dr Massey mentions - involving complex brain surgery to deliver gene therapy - were a success, slowing HD progression by up to 75%. Tom explains the science behind this advance, focusing on the role of DNA repair mechanisms.

We talk about the big ethical issues around pre-symptomatic testing and hear Dr Massey’s reflection on the "awe-inspiring" families and patients who volunteer for invasive trials, driven by hope for their children and grandchildren. Tom talks about how his research is motivated by his relationships with his patients and how witnessing their decline has only driven him further in his search for new treatments.

This is an essential listen for anyone connected to HD or interested in the future of neurodegenerative disease treatment.

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