BrainSherpa Changes and Cognitive Enhancement with Transcranial Photobiomodulation

Transcranial photobiomodulation (tPBM), a non-invasive technique using near-infrared light to stimulate brain function, is explored for its effects on cognitive performance, specifically reaction time as measured by the Psychomotor Vigilance Test (PVT). Studies show tPBM improves PVT scores, although statistical significance isn't always achieved. The mechanism involves activating cytochrome c oxidase and modulating synaptic plasticity, potentially enhancing neuronal activity and impacting cerebral metabolism. While tPBM demonstrates a high safety profile, further research, including larger randomized controlled trials, is needed to confirm its efficacy and explore its applications in treating cognitive impairment and neurodegenerative diseases. Future directions include optimizing treatment protocols and exploring nanotechnology integration for enhanced drug delivery.