Biomarkers in MS (NfL, GFAP, Kappa Light Chains): when they actually change decisions?

Welcome to another episode of the BeeWellwithMS Podcast, hosted by Dr. Agne Straukiene. This special episode delves into the world of biomarkers in multiple sclerosis (MS). Learn about the silent signals inside our bodies that help understand inflammation, disease progression, and responses to treatment even before symptoms occur. Dr. Sharmilee Gnanapavan, a renowned neurologist and expert in biomarker science, joins us to discuss key biomarkers like neurofilament, kappa light chain, GFAP, and more. Whether you are living with MS, a caregiver, or a healthcare provider, this episode offers valuable insights into how these biomarkers can facilitate a more personalised, predictive, and preventative approach to MS care. Stay informed about the latest in MS symptoms, treatment, diet, exercise, and smoldering MS. Don't miss this conversation that's shaping the future of MS care.

00:00 Introduction to the Podcast and Today's Topic
00:46 Meet Dr. Sharmilee Gnanapavan
02:48 Understanding Biomarkers in MS
10:24 Kappa Light Chain Free Index Explained
16:33 Neurofilament: A Key Biomarker
24:42 GFAP and Progressive MS
33:26 Emerging Biomarkers: Chitinase-3-like Protein
35:31 CXCL13 and B-Cell Activity
38:38 Matrix Metalloproteinase-9 (MMP-9)
41:28 The Future of Biomarkers in MS
47:30 Conclusion and Final Thoughts

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