Ch 38/39 provides an in-depth look at antibiotic therapy, focusing on different classes of antibacterial drugs. It discusses general principles of antibiotic use, including how they work and the differences between empiric, definitive, and prophylactic therapy. The text also addresses crucial considerations such as drug resistance, adverse effects, drug interactions, and specific host factors influencing treatment outcomes. Detailed information is provided for sulfonamides, penicillins, cephalosporins, carbapenems, monobactams, macrolides, and tetracyclines, including their mechanisms of action, indications, contraindications, and pharmacokinetic profiles. Finally, the text includes nursing considerations for administering these medications, emphasizing assessment, implementation, and evaluation of antibiotic therapy.

Ch. 48 discusses three conditions affecting the pancreas and biliary system: acute and chronic pancreatitis, pancreatic cancer, and gallbladder problems including cholelithiasis and cholecystitis, as well as gallbladder cancer. For each condition, the text outlines the etiology and pathophysiology, describing what causes the condition and how it affects the body. Clinical manifestations are detailed, covering the signs and symptoms experienced by patients. The document also reviews diagnostic studies used to identify these illnesses, potential complications that can arise, and various interprofessional and nursing care approaches, including medical, surgical, and nutritional therapies.

Ch. 46 offers a comprehensive overview of various upper gastrointestinal (GI) disorders, focusing on their etiology, pathophysiology, clinical manifestations, and management. Key topics include the common issues of nausea and vomiting, as well as more specific conditions such as oral cancer, gastroesophageal reflux disease (GERD), hiatal hernia, esophageal cancer, and peptic ulcer disease (PUD). The material also addresses complications associated with these disorders, including GI bleeding, perforation, and gastric outlet obstruction, along with the nursing and interprofessional care required for patients experiencing these issues. Finally, the text briefly touches upon gastritis, foodborne illnesses, and the implications of gastric surgery.