Behind the Insights: Ep 03 Decoding Treatment-Resistant Depression with Carl Marci, MD
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In this episode of Behind the Insights, Carl D. Marci, MD, Chief Clinical Officer and Managing Director of Mental Health and Neuroscience at OM1, explores the complexities of Treatment-Resistant Depression (TRD) and how OM1’s AI-driven models are reshaping the way we identify and treat patients. Discover how real-world data, clinician attestation, and unstructured clinical notes are unlocking hidden patterns in mental health care, and what the future holds for AI in mental health.
0:00 Intro
0:37 What is Treatment-Resistant Depression and why is it so challenging to define and detect?
1:13 How common is it for patients to experience failure with multiple treatments?
1:43 Highlighting “psychiatrist-attested TRD” with AI and unstructured clinical notes
2:38 Can you walk us through how you know which definition of TRD is correct?
3:35 How do you see AI evolving in the discovery and treatment of TRD?
4:05 How do we ensure trust, accuracy, and clinical relevance when using AI to identify patients?
4:38 The future of mental health and AI
5:04 Final Thoughts
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#mentalhealth #depression #treatmentresistantdepression #ai #realworlddata #rwd #realworldevidence #rwe #clinicalresearch #pharma