Adult CNS Radiation Oncology: Principles and Practice

A comprehensive overview of radiation oncology for central nervous system (CNS) tumors, focusing heavily on diagnosis, grading, and multimodal treatment strategies. Several types of tumors are discussed, including meningiomas, craniopharyngiomas, various gliomas, spinal cord tumors, and metastatic brain disease, often referencing the WHO grading criteria and prognostic factors like the extent of surgical resection. A significant portion of the text details radiation techniques such as Stereotactic Radiosurgery (SRS), Intensity-Modulated Radiation Therapy (IMRT), and Proton Beam Therapy, comparing their application, dose prescriptions, and the critical importance of Organ-at-Risk (OAR) dose constraints to manage potential radiation toxicity like radionecrosis and neurocognitive decline. Ultimately, the material highlights the need for precise planning and sophisticated delivery systems to optimize tumor control while minimizing long-term patient morbidity.

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