91: NAD+ Metabolism and Mitochondrial Homeostasis in Aging and Disease

This episode does a deep dive into an article on Nicotinamide adenine dinucleotide (NAD+), which is an essential coenzyme that facilitates vital biological processes such as energy production, DNA repair, and metabolic balance. Because NAD+ levels naturally decline with age, researchers are investigating various precursors like NR and NMN, alongside enzyme inhibitors, to restore cellular health.

Yusri K, Jose S, Vermeulen KS, Tan TCM, Sorrentino V. The role of NAD+ metabolism and its modulation of mitochondria in aging and disease. npj Metab Health Dis. 2025;3:26. doi:10.1038/s44324-025-00067-0

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