S1 Episode 5: 50+ Years in the Making, RSV Vaccine Arrives

Dr Barney Graham, Time's 2021 Hero of the Year for his work on the COVID-19 vaccine, joins Dr Forest Arnold in this episode covering the groundbreaking work done to develop an RSV vaccine.

Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/985981). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.

Resources

Respiratory Syncytial Virus Infection https://emedicine.medscape.com/article/971488-overview

Field Evaluation of a Respiratory Syncytial Virus Vaccine and a Trivalent Parainfluenza Virus Vaccine in a Pediatric Population https://pubmed.ncbi.nlm.nih.gov/4305200/

Structure and Function of Respiratory Syncytial Virus Surface Glycoproteins https://pubmed.ncbi.nlm.nih.gov/24362685/

Identification and Characteristics of Fusion Peptides Derived From Enveloped Viruses https://pubmed.ncbi.nlm.nih.gov/34497798/

Brief History and Characterization of Enhanced Respiratory Syncytial Virus Disease https://pubmed.ncbi.nlm.nih.gov/26677198/

Structure-based Design of a Fusion Glycoprotein Vaccine for Respiratory Syncytial Virus https://pubmed.ncbi.nlm.nih.gov/24179220/

FDA Approves First Respiratory Syncytial Virus (RSV) Vaccine https://www.fda.gov/news-events/press-announcements/fda-approves-first-respiratory-syncytial-virus-rsv-vaccine

Vaccine-associated Enhanced Disease: Case Definition and Guidelines for Data Collection, Analysis, and Presentation of Immunization Safety Data https://pubmed.ncbi.nlm.nih.gov/33637387/

Th1 and Th2 Responses: What Are They? https://pubmed.ncbi.nlm.nih.gov/10938051/

Cytokine Pathways in Allergic Disease https://pubmed.ncbi.nlm.nih.gov/22301949/