344. Cardiology: Reinventing the EKG: A Conversation with Crimson Scientific Founders Dr. Michael Cetta & Mark Zachary.
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In this episode, we sit down with Dr. Michael Cetta (CEO) and Mark Zachary (COO) of Crimson Scientific. Hear how an ER doc's daily frustration with tangled EKG wires and adhesive electrodes led to a partnership with a visionary engineer from MIT. They break down why the 12-lead EKG process hasn't changed since 1938 and how their reusable, dry-electrode pad aims to make it faster, simpler, and more accurate. Learn about their regulatory pathway, why they're pivoting to ambulatory care as a beachhead, and the long-term vision of embedding additional sensors into their platform. This is a masterclass in medtech problem-solving, founder symbiosis, and reimagining a foundational diagnostic tool.
Episode Breakdown:
00:00- Intro – Why EKGs Are Still Broken in 2025
00:46- Welcome to The State of MedTech
01:48- Dr. Michael Cetta’s Journey: From Engineer to ER Physician
05:05- Life in Emergency Medicine & Scaling Healthcare Organizations
08:55- Meeting at MIT: The Birth of Crimson Scientific
11:48- Clinician + Engineer Co-Founder Dynamic
14:10- The Real Problem: Why Capturing an EKG Is So Frustrating
16:45- A 1938 Technology Still Used Today
18:55- Why Medtech Innovation Stagnates
21:10- How Big Is the EKG Market? (2M+ Per Day)
23:30- Reimagining the EKG: A New Form Factor
25:45- The Reusable ECG Pad Explained
28:30- Human-Centered Design Challenges in Medical Devices
31:00- Regulatory Pathway & FDA Strategy
34:10- Funding, Accelerators & Early Traction
37:10- Go-to-Market Strategy: Hospitals vs Ambulatory Care
40:50- Future Vision: Multi-Sensor Wearable Diagnostics
43:00- IP Strategy & Acquisition Potential
45:00- Final Thoughts & Where to Follow Crimson Scientific
47:00- Closing Remarks & Podcast Call-to-Action
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