What if fatigue, fear, and even failure aren’t real limits — but signals from the brain trying to protect us?

Nick Thompson, CEO of The Atlantic and former Editor-in-Chief of Wired reveals the surprising psychology behind fatigue, focus, and fear — and how our biggest limits often come from within.

Nick isn’t just one of the most thoughtful leaders in media — he’s also a record-breaking ultramarathoner who’s learned that endurance begins in the mind.

This conversation will change how you think about performance, aging, and the power of effort itself.

Nick's wonderful new book is The Running Ground.

We’re told youth is life’s peak — but what if that story is wrong?

Stanford psychologist Laura Carstensen reveals how time itself reshapes what we value and how we find meaning. Her research offers profound lessons for living well at every age — and for finding more meaning in the moments we have.

It’s a conversation that will change how you think about time, happiness, and life itself.

We’ve entered a new age. Where nature once took a million years to make a few genetic changes, scientists can now make billions in an afternoon — and even imagine adapting humans for life beyond Earth.

George Church, a Harvard geneticist, pioneer of the Human Genome Project, and founder of more than 50 biotech companies, helped lay the foundation for CRISPR, personal genomics, and even de-extinction.

In this episode, he explains how biotechnology, AI, and materials science are converging to transform life itself - from reversing aging and curing disease to resurrecting lost species like the woolly mammoth, and one day, helping humanity thrive among the stars.