155: Itchy Palms in Pregnancy? Intrahepatic Cholestasis (ICP) Explained + When Delivery Is Recommended
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Roxanne breaks down Intrahepatic Cholestasis of Pregnancy (ICP) —a pregnancy-specific liver condition (about 2–3% of pregnancies) where bile acids build up in the bloodstream, often causing intense itching on palms/soles with no rash. She reviews other possible symptoms (jaundice, dark urine, light stools, fatigue, right upper quadrant pain), how diagnosis is made with symptoms plus bile acid labs (and sometimes liver enzymes), and how treatment depends on bile acid levels. Roxanne discusses options such as meds to lower bile acids and improve itching, fetal monitoring (NSTs/BPPs), and sometimes induction as early as 36 weeks—especially if bile acids are over 100. She explains baby risks (preterm birth, respiratory distress, stillbirth), including stillbirth rates. ICP usually resolves after birth but can recur (40–60%).
00:00 Welcome and Overview
00:16 Meet the Hosts
01:04 ICP Symptoms and Why It Matters
01:29 What ICP Is in the Liver
02:15 Risks for Mom and Baby
03:32 Other Signs and Diagnosis
04:22 Treatment and Monitoring Plan
05:24 Bile Acid Levels and Induction Timing
06:49 Stillbirth Risk Numbers Explained
09:08 Quick ICP Recap
11:20 After Birth and Future Pregnancies
11:59 Questions, Course, and Wrap-Up
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