What Changes About Executive Function After 40 with Dr. Brandy Callahan

Here's something nobody tells you about aging with ADHD: the part that feels like decline might not be decline at all. It might be retirement. Or perimenopause. Or just the fact that the external structure that quietly managed your symptoms for thirty years finally disappeared — and nobody warned you it was doing that much work. The question isn't whether your brain is changing. It is. The question is whether you understand why, and what the research actually says about where it leads.

Dr. Brandy Callahan is a clinical neuropsychologist, Canada Research Chair in Adult Clinical Neuropsychology, and the founder of the LiBra Lab — the Lifespan Brain Health Lab at the University of Calgary. Her research sits at the intersection most researchers haven't bothered to explore: what happens to the ADHD brain across decades, and specifically, what connects ADHD to elevated dementia risk. What she's finding — about allostatic burden, about the gap between how people perform in a lab versus how they function in a grocery store on a Sunday afternoon, about what a lifetime of navigating a neurotypical world may actually cost the brain biologically — is the conversation this series has been building toward. There is hard news in here. There is also, genuinely, a lot of hope.

Guest Spotlight

Dr. Brandy Callahan, PhD, RPsych is a clinical neuropsychologist, Associate Professor of Psychology at the University of Calgary, and a Canada Research Chair in Adult Clinical Neuropsychology. She is the founder and principal investigator of the LiBra Lab — the Lifespan Brain Health Lab — which focuses specifically on ADHD in women and in older adulthood, and she came to ADHD research not through personal experience but through a memory clinic, where she kept meeting older adults being evaluated for dementia who turned out to have lived their whole lives with undiagnosed ADHD. Her current research is investigating what may drive elevated dementia risk in adults with ADHD — including allostatic burden, cerebral small vessel disease, and the biological cost of decades of chronic stress. She is also currently running ADHD Her, an online study about girls and women with ADHD across the lifespan, open to participants from age 8 to 87. Learn more at libralab.ca, and find the ADHD Her study by searching "ADHD Her" online.

Links & Notes

• LiBra Lab
• ADHD Her Study (online, open to participants ages 8-87
• LiBra Lab participant registry (RADAR)
• Support the Show on Patreon
• Dig into the podcast Shownotes Database

• (00:00) - Welcome to Taking Control: The ADHD Podcast
• (05:56) - What does a research neuropsychologist actually do?
• (08:34) - How does EF Age?
• (15:01) - Charting the Decades
• (22:22) - The Shame Cycle... Missing in the Lab
• (23:39) - Alostatic Burden
• (37:06) - So... where's the hope?

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