This rated about 3.5 stars on my scale. It would have been a 3 from an experienced author, but as this is Frost's first novel, I'll round up to 4.
Frost gets a lot of things right. Pacing is good; the action moves without becoming overwhelming, and there aren't any plodding moments. The cast of characters is fairly small and relatively well-defined; the reader is not likely to lose track of who's speaking or what's going on. The writer posits a Buffy-esque world where supernatural beings are somewhat of an open secret.
Most of the bad is the product of this being a freshman effort, and the balancing act necessary to provide adequate characterization without delving into numbing detail. The story features lycanthropes, vampires, DNA sequencing, and other mumbo-jumbo. Unfortunately, the story loses steam whenever we get dragged into the sci-fi expostulations; it's not real science, and there aren't any 'rules' in the world Frost has established with regards to how it works. Thus, the reader can't really do anything with these bits. She'd do well to read some Sanderson, and find a happy place about halfway between Sanderson's overly-long worldbuilding and the minimal framework she established here.
The love for Joss Whedon shines through; it wouldn't surprise me to learn that Frost wrote this while watching Buffy or Firefly reruns. Some of the banter she writes resonates; some misses its mark.
Along those same lines, no discussion or backstory is provided. We've got two very rich guys (one protagonist, one antagonist) with no explanation as to how they became rich; the primary protagonist is a werewolf and we never hear how she became such. There's also never any sense of danger; the stakes are the lives of a couple of people.
Frost, fortunately, doesn't suffer from the same squeamishness some of her colleagues have; characters do perish.
Overall, I think Frost has a lot of promise if she can flesh out her writing a little bit more. Her background in short stories may be holding her back here; she needs to suppress the instinct to edit too much out and let some of the detail stand.