Other people have covered the details of the book well, so I will compare it to other popular biographies about the Founding Fathers written recently to give the reader an idea of what to expect. The trend in biographies lately seems to be elegant and almost novelistic prose. This book is written in a very different style: simple but not simplistic, accessible but not unintelligent. An unusual aspect is that rather than let one subject flow into another, the chapters are further separated into subheadings (e.g. "The American Philosophical Society", "Supplying General Braddock").
The author previously wrote a biography of Steve Jobs, and clearly has an interest in business. Much time is spent on Franklin's early years as a businessman, which I did not find as interesting as his politics. Much time is spent on British colonial economic policy, which I did find very interesting and informative. Additionally, it helped explain why the Tea Partiers were so violently opposed to the taxes and duties. The British government had enacted many policies to keep the colonies economically dependent on the mother country, such as outlawing ironworks in the colonies and suppressing manufacturing. I've read quite a few books about the Revolution and this was the most unexpectedly edifying on the motivations of the rebels in that aspect. This book justifies it's price on that subject alone. (Those uncomfortable with economics should know it was explained clearly enough that I could understand it well, despite having never taken an economics course.)
Additionally, Franklin finally gets his due as a world-class scientist in this biography. As a scientist myself, I wish more had gone into the process of his many discoveries, but it seems likely that there just wasn't enough source material to expand.
A note of criticism: in terms of psychological insight, the book leaves you a little bit wanting. His personal relationships with both men and women are notably detached and a little cold, but no real explanation is given for why this should be so for such an extroverted and warm man. The book quotes the opinion of other commentarors, such as conservative columnist David Brooks, quite a few times on the nature of his political beliefs. I would have preferred the authors own interpretations.
The description of Franklin's transition from a peacemaker who finds himself the target of anger from American rebels for being too inclined to seek compromise- to one of the most passionate voices for independence is elegantly done. When I finished the book I felt like I had real understanding of Franklin as a person full of contractions. A man who loathed conflict but supported a revolution, who wrote The Way to Wealth but was an ardent champion of the common man, who was the darling of the French Court but disliked aristocracy... In other words, a real person, not a cardboard cutout.