In 2006, the Wall Street pioneer and philanthropist Ray Chambers flicked through some holiday snapshots taken by a friend and remarked on the placid beauty of a group of sleeping Malawian children. "They're not sleeping," his friend told him. "They're in malarial comas. A few days later, they were all dead." This moment sparked Chambers' determination to coordinate an unprecedented, worldwide effort to eradicate a disease that has haunted humanity since before the advent of medicine.