
Transformer
The Deep Chemistry of Life and Death
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Narrated by:
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Richard Trinder
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By:
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Nick Lane
For decades, biology has been dominated by the study of genetic information. Information is important, but it is only part of what makes us alive. Our inheritance also includes our living metabolic network, a flame passed from generation to generation, right back to the origin of life. In Transformer, biochemist Nick Lane reveals a scientific renaissance that is hiding in plain sight-how the same simple chemistry gives rise to life and causes our demise.
Lane is among the vanguard of researchers asking why the Krebs cycle, the "perfect circle" at the heart of metabolism, remains so elusive more than eighty years after its discovery. Transformer is Lane's voyage, as a biochemist, to find the inner meaning of the Krebs cycle-why it is still spinning at the heart of life and death today.
Transformer unites the story of our planet with the story of our cells-what makes us the way we are, and how it connects us to the origin of life. Enlivened by Lane's talent for distilling and humanizing complex research, Transformer is a must-listen for anyone fascinated by biology's great mysteries. Life is at root a chemical phenomenon: this is its deep logic.
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The epilogue hints at what I hope will be the direction of Lane’s future writings. I recommend reading it before the rest of the book and then again at the end.
Excellent Exploration of the Krebs Cycle
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I'm a little disappointed that the cool FAD small molecule is not mentioned in the electron transfers, FAD is really the electron donor in most cases not NADPH, the latter donates a hydride, while the FAD takes the hydride and split it into electrons and a proton.
Great and interesting book, I learnt a lot
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A great story of life
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Don’t miss out this essential book!
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Great Book for Geneticists and Microbiologists
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Great synthesis of important aspects of biochemistry.
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Like his other books, superb
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Are used immersive learning for this book it was excellent
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Great book but a difficult audiobook
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Completely transformed my sense of being alive
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