Nearly every American knows someone who has been affected by the opioid crisis. Addiction is a trans-partisan issue that impacts individuals from every walk of life. Millions of Americans are tired of watching their loved ones die while politicians ignore this issue. Where is the solution? Where is the hope? Where's the outrage? Ryan Hampton understands firsthand how easy it is to develop a dependency on opioids, and how destructive it can quickly become. Now, he is waging a permanent campaign to change our way of thinking about and addressing addiction in this country.

Between 1999 and 2017, an estimated 250,000 Americans died from overdoses involving prescription painkillers, a plague ignited by Purdue Pharma’s aggressive marketing of OxyContin. Families, working class and wealthy, have been torn apart, businesses destroyed, and public officials pushed to the brink. Meanwhile, the drugmaker’s owners, Raymond and Mortimer Sackler, whose names adorn museums worldwide, made enormous fortunes from the commercial success of OxyContin.

From “one of the bravest, smartest writers about addiction anywhere” (Johann Hari, New York Times best-selling author) - the untold story of harm reduction, a surprisingly simple idea with enormous power.

From the New York Times best-selling author of Dreamland, a searing follow-up that explores the terrifying next stages of the opioid epidemic and the quiet yet ardent stories of community repair.

The prize-winning and best-selling author of Say Nothing presents a grand, devastating portrait of three generations of the Sackler family, famed for their philanthropy, whose fortune was built by Valium and whose reputation was destroyed by OxyContin. Empire of Pain is a masterpiece of narrative reporting and writing, exhaustively documented and ferociously compelling.

From the prize-winning, New York Times bestselling author of Empire of Pain and Say Nothing—and one of the most decorated journalists of our time—twelve enthralling stories of skulduggery and intrigue.

Years before the name Alex Murdaugh was splashed across every major media outlet in America, local South Carolina journalist Mandy Matney had an instinct that something wasn’t right in the Lowcountry. The powerful Murdaugh dynasty had dominated rural South Carolina for generations. No one dared to cross them.

On October 12, 1972, a plane carrying a team of young rugby players crashed into the remote, snow-peaked Andes. Out of the 45 original passengers and crew, only 16 made it off the mountain alive. For 10 excruciating weeks, they suffered deprivations beyond imagining, confronting nature head-on at its most furious and inhospitable. And to survive, these men and women not only had to keep their faith; they had to make an impossible decision: Should they eat the flesh of their dead friends?

In her gripping, necessary, and deeply humane follow-up to the New York Times bestseller Dopesick, journalist Beth Macy brings us to the next frontier of the opioid crisis, telling the story of the everyday heroes fighting to stem the tide of drug overdose in communities that are too often left to fend for themselves, and of the activists and relatives of the dead who are still struggling for accountability in America’s courts. Like the treatment innovators she profiles, Beth Macy meets the opioid crisis where it is—not where we think it should be or wish it was.

In 1929, in the blue-collar city of Portsmouth, Ohio, a company built a swimming pool the size of a football field; named Dreamland, it became the vital centre of the community. Now, addiction has devastated Portsmouth, as it has hundreds of small rural towns and suburbs across America—addiction like no other the country has ever faced. How that happened is the riveting story of Dreamland.

In a pharmacy in Kermit, West Virginia, 12 million opioid pain pills were distributed in just three years to a town with a population of 382 people. One woman, after losing her brother to overdose, was desperate for justice. Debbie Preece’s fight for accountability for her brother’s death took her well beyond the Sav-Rite Pharmacy in coal country, ultimately leading to three of the biggest drug wholesalers in the country. She was joined by a crusading lawyer and by local journalist Eric Eyre, who uncovered a massive opioid pill-dumping scandal.

In the 1950s, a young Indianapolis minister named Jim Jones preached a curious blend of the gospel and Marxism. His congregation was racially mixed, and he was a leader in the early civil rights movement. Eventually, Jones moved his church, Peoples Temple, to northern California, where he got involved in electoral politics and became a prominent Bay Area leader. But underneath the surface lurked a terrible darkness.

Pharmaceutical breakthroughs such as antibiotics and vaccines rank among some of the greatest advancements in human history. Yet, exorbitant prices for life-saving drugs, safety recalls affecting tens of millions of Americans, and soaring rates of addiction and overdose on prescription opioids have caused many to lose faith in drug companies. Now, Americans are demanding a national reckoning with a monolithic industry.

The opioid epidemic has been described as "one of the greatest mistakes of modern medicine." But calling it a mistake is a generous rewriting of the history of greed, corruption, and indifference that pushed the US into consuming more than 80 percent of the world's opioid painkillers. Journeying through lives and communities wrecked by the epidemic, Chris McGreal reveals not only how Big Pharma hooked Americans on powerfully addictive drugs but the corrupting of medicine and public institutions that let the opioid makers get away with it.

The daughter of immigrants and civil rights activists, Vice President Kamala Harris was raised in an Oakland, California, community that cared deeply about social justice. As she rose to prominence as one of the political leaders of our time, her experiences would become her guiding light as she grappled with an array of complex issues and learned to bring a voice to the voiceless. In The Truths We Hold, she reckons with the big challenges we face together.