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Unnecessary Expense
- An Antidote for the Billion Dollar Drug Problem
- Narrated by: TJ Oberholzer
- Length: 3 hrs and 58 mins
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Publisher's summary
The drug development process in the United States has become so weighted down by a business-as-usual paradigm that an average of more than two billion dollars is spent to secure FDA approval for every new drug. Because the investment required is so extreme, drug development companies are understandably focused on discovering and developing drugs designed for large patient populations: diseases experienced by millions, such as high blood pressure, diabetes, or some of the more common cancers.
In Unnecessary Expense, Dr. Charles Theuer, CEO of TRACON Pharmaceuticals, outlines the problem and offers a solution: an aligned and streamlined model that emphasizes quality and reduces the time and cost of drug development, while also harnessing global innovation to benefit patients with rare diseases in urgent need of new treatments. Here Dr. Theuer shows the value of a pharmaceutical paradigm shift, to enable the development of drugs for patients who need them, at a fraction of the time and cost.
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- Unabridged
-
Overall4 out of 5 stars 143
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Performance4.5 out of 5 stars 126
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Story4 out of 5 stars 125
Ezekiel J. Emanuel, a professor of medical ethics and health policy at the University of Pennsylvania who also served as a special adviser to the White House on health-care reform, has written a brilliant diagnostic explanation of why health care in America has become such a divisive social issue, how money and medicine have their own American story, and why reform has bedeviled presidents of the left and right for more than one hundred years.
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2 out of 5 stars
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The book lacks integrity
- By Richard M. Shaner on 06-02-16
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Power and Prediction
- The Disruptive Economics of Artificial Intelligence
- By: Ajay Agrawal, Joshua Gans, Avi Goldfarb
- Narrated by: Tom Beyer
- Length: 10 hrs and 7 mins
- Unabridged
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Overall4.5 out of 5 stars 84
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Performance4.5 out of 5 stars 74
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Story4.5 out of 5 stars 74
In their bestselling first book, Prediction Machines, eminent economists Ajay Agrawal, Joshua Gans, and Avi Goldfarb explained the simple yet game-changing economics of AI. Now, in Power and Prediction, they go deeper, examining the most basic unit of analysis: the decision. The authors explain that the two key decision-making ingredients are prediction and judgment, and we perform both together in our minds, often without realizing it.
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5 out of 5 stars
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Inspire system thinking with informative examples
- By Lucy A. Pithecus on 11-16-22
By: Ajay Agrawal, and others
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The Language of Life
- DNA and the Revolution in Personalized Medicine
- By: Francis S. Collins
- Narrated by: Greg Itzin
- Length: 10 hrs and 45 mins
- Unabridged
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Overall4 out of 5 stars 148
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Performance4.5 out of 5 stars 99
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Story4 out of 5 stars 97
A scientific and medical revolution has crept up on us, based on study after study, from hundreds of laboratories around the world. It is no longer just a theoretical shift: every one of us will be touched by it, and many of us already have been. The meaning of disease, our understanding of the human body, and crucial decisions about what we all need to know and what choices we make about our health are at stake. Welcome to the new world of personalized medicine.
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5 out of 5 stars
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The future of medicine
- By Ronald E on 04-12-10
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Attacker's Advantage
- Turning Uncertainty into Breakthrough Opportunities
- By: Ram Charan
- Narrated by: Mark Bramhall
- Length: 6 hrs and 8 mins
- Unabridged
-
Overall4 out of 5 stars 80
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Performance4 out of 5 stars 65
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Story4 out of 5 stars 66
In The Attacker's Advantage, Charan reveals the upside of uncertainty for those leaders who are nimbly positioned to anticipate the catalysts of disruption and embrace change. He updates and adapts the principles of his previous best sellers to address the current turbulent business environment, cutting through the veil of complexity to concentrate on the new customer needs and expectations and providing the tools for corporate leaders to take their companies to a higher level.
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4 out of 5 stars
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Fantastic book - volume lower than usual
- By James Gajewski on 06-14-15
By: Ram Charan
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The Wide Lens
- A New Strategy for Innovation
- By: Ron Adner
- Narrated by: Walter Dixon
- Length: 6 hrs and 19 mins
- Unabridged
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Overall4.5 out of 5 stars 95
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Performance4.5 out of 5 stars 87
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Story4.5 out of 5 stars 86
How can great companies do everything right - identify real customer needs, deliver excellent innovations, beat their competitors to market - and still fail? The sad truth is that many companies fail because they focus too intensely on their own innovations, and then neglect the innovation ecosystems on which their success depends. In our increasingly interdependent world, winning requires more than just delivering on your own promises. It means ensuring that a host of partners - some visible, some hidden - deliver on their promises, too.
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5 out of 5 stars
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Great book
- By Anonymous User on 12-25-21
By: Ron Adner
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The Future of the Professions
- How Technology Will Transform the Work of Human Experts
- By: Richard Susskind, Daniel Susskind
- Narrated by: John Lee
- Length: 12 hrs and 39 mins
- Unabridged
-
Overall4 out of 5 stars 272
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Performance4 out of 5 stars 225
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Story4 out of 5 stars 224
This book predicts the decline of today's professions and describes the people and systems that will replace them. In an Internet society, according to Richard Susskind and Daniel Susskind, we will neither need nor want doctors, teachers, accountants, architects, the clergy, consultants, lawyers, and many others to work as they did in the 20th century.
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3 out of 5 stars
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I Hope It's Not All True
- By John on 05-01-16
By: Richard Susskind, and others
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Jump-Starting America
- How Breakthrough Science Can Revive Economic Growth and the American Dream
- By: Jonathan Gruber, Simon Johnson
- Narrated by: Robert Fass
- Length: 9 hrs and 57 mins
- Unabridged
-
Overall4.5 out of 5 stars 76
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Performance5 out of 5 stars 59
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Story4.5 out of 5 stars 59
The untold story of how America once created the most successful economy the world has ever seen and how we can do it again.
By: Jonathan Gruber, and others
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Trick or Treatment
- The Undeniable Facts about Alternative Medicine
- By: Edzard Ernst, Simon Singh
- Narrated by: Dennis Kleinman
- Length: 12 hrs and 33 mins
- Unabridged
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Overall4.5 out of 5 stars 49
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Performance4.5 out of 5 stars 36
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Story4.5 out of 5 stars 35
Whether you are an ardent believer in alternative medicine, a skeptic, or are simply baffled by the range of services and opinions, this guide lays to rest doubts and contradictions with authority, integrity, and clarity. In this groundbreaking analysis, over 30 of the most popular treatments - acupuncture, homeopathy, aromatherapy, reflexology, chiropractic, and herbal medicines - are examined for their benefits and potential dangers. Questions answered include: What works and what doesn't? What are the secrets, and what are the lies?
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5 out of 5 stars
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Well researched
- By Erik J. Rasmussen on 09-09-20
By: Edzard Ernst, and others
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Where Does It Hurt?
- An Entrepreneur's Guide to Fixing Health Care
- By: Jonathan Bush, Stephen Baker
- Narrated by: Patrick Lawlor
- Length: 7 hrs and 21 mins
- Unabridged
-
Overall4.5 out of 5 stars 144
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Performance4.5 out of 5 stars 113
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Story4.5 out of 5 stars 115
A bold new remedy for the sprawling and wasteful health care industry. In this provocative book, Jonathan Bush, cofounder and CEO of athenahealth, calls for a revolution in health care to give customers more choices, freedom, power, and information, and at far lower prices.
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2 out of 5 stars
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No critical thinking
- By Steve from MD on 07-31-14
By: Jonathan Bush, and others
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The Antidote
- Inside the World of New Pharma
- By: Barry Werth
- Narrated by: Sean Pratt
- Length: 16 hrs and 27 mins
- Unabridged
-
Overall4 out of 5 stars 75
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Performance4 out of 5 stars 64
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Story4 out of 5 stars 65
In 1989, the charismatic Joshua Boger left Merck, then America's most admired business, to found a drug company that would challenge industry giants and transform health care. Barry Werth described the company's tumultuous early days during the AIDS crisis in The Billion-Dollar Molecule, a celebrated classic of science and business journalism. Now he returns to tell a riveting story of Vertex's bold endurance and eventual success.
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2 out of 5 stars
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For me this was not interesting
- By Yan on 06-26-17
By: Barry Werth
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Out-Innovate
- How Global Entrepreneurs - from Delhi to Detroit - Are Rewriting the Rules of Silicon Valley
- By: Alexandre Lazarow
- Narrated by: Dennis Boutsikaris, Alexandre Lazarow
- Length: 7 hrs and 42 mins
- Unabridged
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Overall4.5 out of 5 stars 45
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Performance5 out of 5 stars 33
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Story4.5 out of 5 stars 34
As venture capitalist Alexandre Lazarow shows in this insightful and instructive book, this Silicon Valley "gospel" is due for a refresh - and it comes from what he calls the "frontier", the growing constellation of startup ecosystems, outside of the Valley and other major economic centers, that now stretches across the globe. The frontier is a truly different world where startups often must cope with political or economic instability and lack of infrastructure, and where there might be little or no access to angel investors, venture capitalists, or experienced employee pools.
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5 out of 5 stars
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Great material for SF and Frontier entrepreneurs!
- By Brett Fulmer on 04-15-20
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The Fourth Industrial Revolution
- By: Klaus Schwab
- Narrated by: Nicholas Guy Smith
- Length: 5 hrs and 32 mins
- Unabridged
-
Overall4 out of 5 stars 646
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Performance4.5 out of 5 stars 548
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Story4 out of 5 stars 548
World-renowned economist Klaus Schwab, founder and executive chairman of the World Economic Forum, explains that we have an opportunity to shape the fourth industrial revolution, which will fundamentally alter how we live and work.
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1 out of 5 stars
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Friendly reminding : On August 15th, 1971, the dec
- By steve white on 03-24-21
By: Klaus Schwab
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Unaccountable
- What Hospitals Won't Tell You and How Transparency Can Revolutionize Health Care
- By: Marty Makary
- Narrated by: Robertson Dean
- Length: 7 hrs and 16 mins
- Unabridged
-
Overall4.5 out of 5 stars 235
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Performance4.5 out of 5 stars 204
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Story4.5 out of 5 stars 206
Dr. Marty Makary is co-developer of the life-saving checklist outlined in Atul Gawande's best-selling The Checklist Manifesto. As a busy surgeon who has worked in many of the best hospitals in the nation, he can testify to the amazing power of modern medicine to cure. But he's also been a witness to a medical culture that routinely leaves surgical sponges inside patients, amputates the wrong limbs, and overdoses children because of sloppy handwriting. Over the last 10 years, neither error rates nor costs have come down, despite scientific progress.
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5 out of 5 stars
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Everyone should read this book.
- By Julie on 06-11-16
By: Marty Makary
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Human + Machine
- Reimagining Work in the Age of AI
- By: Paul R. Daugherty, H. James Wilson
- Narrated by: Jamie Renell
- Length: 5 hrs and 55 mins
- Unabridged
-
Overall4 out of 5 stars 332
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Performance4.5 out of 5 stars 283
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Story4 out of 5 stars 283
Look around you. Artificial intelligence is no longer just a futuristic notion. It's here right now - in software that senses what we need, supply chains that "think" in real time, and robots that respond to changes in their environment. Twenty-first-century pioneer companies are already using AI to innovate and grow fast. The bottom line is this: Businesses that understand how to harness AI can surge ahead. Those that neglect it will fall behind. Which side are you on?
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3 out of 5 stars
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A golf course book
- By C. Surdak on 07-30-18
By: Paul R. Daugherty, and others
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The Price We Pay
- What Broke American Health Care - and How to Fix It
- By: Marty Makary MD
- Narrated by: Marty Makary MD
- Length: 9 hrs and 29 mins
- Unabridged
-
Overall5 out of 5 stars 904
-
Performance5 out of 5 stars 784
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Story5 out of 5 stars 778
One in five Americans now has medical debt in collections and rising health care costs today threaten every small business in America. Dr Makary, one of the nation's leading health care experts, travels across America and details why health care has become a bubble. Drawing from on-the-ground stories, his research and his own experience, The Price We Pay paints a vivid picture of price-gouging, middlemen and a series of elusive money games in need of a serious shake-up.
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5 out of 5 stars
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Very important book!
- By Wayne on 05-17-21
By: Marty Makary MD
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Super Crunchers
- Why Thinking-by-Numbers Is the New Way to Be Smart
- By: Ian Ayres
- Narrated by: Michael Kramer
- Length: 7 hrs and 34 mins
- Unabridged
-
Overall4 out of 5 stars 850
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Performance4.5 out of 5 stars 273
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Story4 out of 5 stars 275
Today, number crunching affects your life in ways you might never imagine. In this lively and groundbreaking new audiobook, economist Ian Ayres shows how today's best and brightest organizations are analyzing massive databases at lightening speed to provide greater insights into human behavior. They are the Super Crunchers.
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5 out of 5 stars
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Great book on
- By Jon on 01-31-08
By: Ian Ayres
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Less Medicine, More Health
- 7 Assumptions That Drive Too Much Medical Care
- By: H. Gilbert Welch
- Narrated by: L. J. Ganser
- Length: 8 hrs and 18 mins
- Unabridged
-
Overall5 out of 5 stars 100
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Performance5 out of 5 stars 90
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Story4.5 out of 5 stars 90
The author of the highly acclaimed Overdiagnosed describes seven widespread assumptions that encourage excessive, often ineffective, and sometimes harmful medical care. You might think the biggest problem in medical care is that it costs too much. Or that health insurance is too expensive, too uneven, too complicated - and gives you too many forms to fill out. But the central problem is that too much medical care has too little value.
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4 out of 5 stars
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The truth will set you free
- By Rene B Milner on 04-01-16
By: H. Gilbert Welch
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