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The Code Breaker
- Jennifer Doudna, Gene Editing, and the Future of the Human Race
- Narrated by: Kathe Mazur
- Length: 16 hrs and 4 mins
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The Code Breaker
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Publisher's summary
The best-selling author of Leonardo da Vinci and Steve Jobs returns with a gripping account of how the pioneering scientist Jennifer Doudna, along with her colleagues and rivals, launched a revolution that will allow us to cure diseases, fend off viruses, and enhance our children.
An Audie Award 2022 Finalist
In the spring of 2012, the Berkeley biochemist Jennifer Doudna and her collaborators turned a curiosity of nature into an invention that will transform the future of the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions. It has already been deployed to cure deadly diseases, fight the coronavirus pandemic of 2020, and make inheritable changes in the genes of babies.
The development of CRISPR and the war against coronavirus will hasten our transition to the next great innovation revolution. The past half-century has been an information-technology era, based on the microchip, the computer, and the internet. Now we are entering an even more momentous era, a life-science revolution. Children who study digital coding will be surpassed by those who study the code of life.
Should we use our new evolution-hacking powers to make us less susceptible to viruses and eliminate dreaded disorders? What a wonderful boon that would be! Right? And what about preventing congenital deafness or blindness? Or being very short? Or being depressed? Hmmm....how should we think about that? Should we allow parents, if they can afford it, to enhance the IQ or height or memory or muscles of their kids?
After helping to discover CRISPR, Doudna became a leader in wrestling with these moral and policy issues. Her life story illustrates that the key to innovation is connecting basic science to our everyday lives - moving discoveries from our labs to our bedsides - in ways that respect our moral values. It’s a thrilling detective tale that involves the most profound wonders of nature, from the origins of life to the future of our species.
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Story4.5 out of 5 stars 30
Lee Hood did that rarest of things. He enabled scientists to see things they couldn't see before and do things they hadn't dreamed of doing. Scientists can now sequence complete human genomes in a day, setting in motion a revolution that is personalizing medicine. Hood, a son of the American West, was an unlikely candidate to transform biology. But with ferocious drive, he led a team at Caltech that developed the automated DNA sequencer, the tool that paved the way for the Human Genome Project.
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4 out of 5 stars
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A Revealing Biography
- By Jean on 07-27-17
By: Luke Timmerman, and others
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p53: The Gene That Cracked the Cancer Code
- By: Sue Armstrong
- Narrated by: Elizabeth Jasicki
- Length: 9 hrs and 55 mins
- Unabridged
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Overall4.5 out of 5 stars 122
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Performance4 out of 5 stars 106
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Story4.5 out of 5 stars 104
p53: The Gene That Cracked the Cancer Code reveals the tale of the search for this gene, as well as the excitement of the hunt for new cures - the hype, the lost opportunities, the blind alleys, and the thrilling breakthroughs. As the long-anticipated revolution in cancer treatment tailored to each individual patient's symptoms starts to take off at last, p53 is still at the forefront of the game. This is a timely tale of scientific discovery and advances in our understanding of a disease that still affects more than one in three of us at some point in our lives.
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5 out of 5 stars
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Excellent story! Unfortunate narration at start
- By Adriana on 12-25-14
By: Sue Armstrong
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A Shot to Save the World
- The Inside Story of the Life-or-Death Race for a COVID-19 Vaccine
- By: Gregory Zuckerman
- Narrated by: Jack Armstrong
- Length: 12 hrs and 6 mins
- Unabridged
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Overall4.5 out of 5 stars 171
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Performance4.5 out of 5 stars 145
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Story4.5 out of 5 stars 144
Few were ready when a mysterious respiratory illness emerged in Wuhan, China, in January 2020. Politicians, government officials, business leaders, and public-health professionals were unprepared for the most devastating pandemic in a century. Many of the world’s biggest drug and vaccine makers were slow to react or couldn’t muster an effective response. It was up to a small group of unlikely and untested scientists and executives to save civilization.
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5 out of 5 stars
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Wow! Do not miss this one.
- By Jacob on 11-18-21
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Rigor Mortis
- How Sloppy Science Creates Worthless Cures, Crushes Hope, and Wastes Billions
- By: Richard Harris
- Narrated by: Joe Delafield
- Length: 5 hrs and 56 mins
- Unabridged
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Overall4.5 out of 5 stars 117
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Performance4.5 out of 5 stars 100
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Story4.5 out of 5 stars 99
American taxpayers spend $30 billion annually funding biomedical research, but over half of these studies can't be replicated due to poor experimental design, improper methods, and sloppy statistics. Bad science doesn't just hold back medical progress, it can sign the equivalent of a death sentence for terminal patients. In Rigor Mortis, Richard Harris explores these urgent issues with vivid anecdotes, personal stories, and interviews with the top biomedical researchers. We need to fix our dysfunctional biomedical system - before it's too late.
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5 out of 5 stars
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Eye opening introduction to biomedical R&D
- By Amazon Customer on 09-18-18
By: Richard Harris
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Plague of Corruption
- Restoring Faith in the Promise of Science
- By: Dr. Judy Mikovits, Kent Heckenlively, Robert F. Kennedy Jr.
- Narrated by: Mariel Hemingway
- Length: 10 hrs and 10 mins
- Unabridged
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Overall5 out of 5 stars 796
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Performance4.5 out of 5 stars 710
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Story5 out of 5 stars 708
Dr. Judy Mikovits is a modern-day Rosalind Franklin, a brilliant researcher shaking up the old boys' club of science with her groundbreaking discoveries. And like many women who have trespassed into the world of men, she uncovered decades-old secrets that many would prefer to stay buried.
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5 out of 5 stars
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If only most of the public knew these facts
- By David Getoff, CCN on 06-18-20
By: Dr. Judy Mikovits, and others
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The Compatibility Gene
- How Our Bodies Fight Disease, Attract Others, and Define Our Selves
- By: Daniel M. Davis
- Narrated by: Christopher Grove
- Length: 7 hrs and 48 mins
- Unabridged
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Overall4.5 out of 5 stars 51
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Performance4.5 out of 5 stars 41
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Story4.5 out of 5 stars 41
Most of the 25,000 genes we possess are the same for all of us. Compatibility genes are those that vary most from person to person and give each of us a unique molecular signature. These genes determine both the extent to which we are susceptible to a vast range of illnesses and the different ways each of us fights disease.
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5 out of 5 stars
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If interested in medicine, got to read
- By Howard Sterling on 06-29-16
By: Daniel M. Davis
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Headstrong
- 52 Women Who Changed Science-and the World
- By: Rachel Swaby
- Narrated by: Lauren Fortgang
- Length: 7 hrs and 1 min
- Unabridged
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Overall4 out of 5 stars 64
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Performance4 out of 5 stars 54
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Story4.5 out of 5 stars 54
In 2013, the New York Times published an obituary for Yvonne Brill. It began: “She made a mean beef stroganoff, followed her husband from job to job, and took eight years off from work to raise three children.” It wasn’t until the second paragraph that readers discovered why the Times had devoted several hundred words to her life: Brill was a brilliant rocket scientist who invented a propulsion system to keep communications satellites in orbit, and had recently been awarded the National Medal of Technology and Innovation.
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4 out of 5 stars
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Role models for young women
- By mtsuda90 on 06-25-16
By: Rachel Swaby
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A Crack in Creation
- Gene Editing and the Unthinkable Power to Control Evolution
- By: Jennifer A. Doudna, Samuel H. Sternberg
- Narrated by: Erin Bennett
- Length: 9 hrs and 22 mins
- Unabridged
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Overall4.5 out of 5 stars 1,348
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Performance4.5 out of 5 stars 1,153
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Story4.5 out of 5 stars 1,152
Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use. Not, that is, until the spring of 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the new gene-editing tool CRISPR - a revolutionary new technology that she helped create - to make heritable changes in human embryos.
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5 out of 5 stars
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In to the abyss we ascend, a scary future
- By Philomath on 06-17-17
By: Jennifer A. Doudna, and others
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The Exceptions
- Nancy Hopkins, MIT, and the Fight for Women in Science
- By: Kate Zernike
- Narrated by: Kathe Mazur
- Length: 14 hrs and 31 mins
- Unabridged
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Overall5 out of 5 stars 74
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Performance5 out of 5 stars 66
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Story5 out of 5 stars 66
In 1963, a female student was attending a lecture given by Nobel Prize winner James Watson, then tenured at Harvard. At nineteen, she was struggling to define her future. She had given herself just ten years to fulfill her professional ambitions before starting the family she was expected to have. For women at that time, a future on the usual path of academic science was unimaginable—but during that lecture, young Nancy Hopkins fell in love with the promise of genetics. Confidently believing science to be a pure meritocracy, she embarked on a career.
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5 out of 5 stars
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Unbelievable
- By Lilit Garibyan on 06-05-23
By: Kate Zernike
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Tomorrowland
- Our Journey From Science Fiction to Science Fact
- By: Steven Kotler
- Narrated by: Tom Parks
- Length: 8 hrs and 58 mins
- Unabridged
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Overall4 out of 5 stars 428
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Performance4.5 out of 5 stars 363
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Story4 out of 5 stars 363
New York Times, Wired, Atlantic Monthly, Discover bestselling author Steven Kotler has written extensively about those pivotal moments when science fiction became science fact...and fundamentally reshaped the world. Now he gathers the best of his best, updated and expanded upon, to guide listeners on a mind-bending tour of the far frontier, and how these advances are radically transforming our lives.
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3 out of 5 stars
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Covers a lot of different topics in many industries
- By ErnieA on 06-27-15
By: Steven Kotler
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Neanderthal Man
- In Search of Lost Genomes
- By: Svante Pääbo
- Narrated by: Dennis Holland
- Length: 10 hrs and 36 mins
- Unabridged
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Overall4 out of 5 stars 773
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Performance4.5 out of 5 stars 686
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Story4 out of 5 stars 690
A preeminent geneticist hunts the Neanderthal genome to answer the biggest question of them all: what does it mean to be human? What can we learn from the genes of our closest evolutionary relatives? Neanderthal Man tells the story of geneticist Svante Pbo’s mission to answer that question, beginning with the study of DNA in Egyptian mummies in the early 1980s and culminating in his sequencing of the Neanderthal genome in 2009.
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5 out of 5 stars
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Excellent science tale
- By Neuron on 01-19-15
By: Svante Pääbo
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101 Theory Drive
- A Neuroscientist's Quest for Memory
- By: Terry McDermott
- Narrated by: Stephen Hoye
- Length: 8 hrs and 55 mins
- Unabridged
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Overall4 out of 5 stars 167
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Performance4 out of 5 stars 63
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Story4 out of 5 stars 65
It's not fiction: Gary Lynch is the real thing, the epitome of the rebel scientist - malnourished, contentious, inspiring, explosive, remarkably ambitious, consistently brilliant. He is one of the foremost figures of contemporary neuroscience, and his decades-long quest to understand the inner workings of the brain's memory machine has begun to pay off.
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5 out of 5 stars
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Pretty Dang Funny
- By Will on 05-14-10
By: Terry McDermott
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Whiplash
- How to Survive Our Faster Future
- By: Joi Ito, Jeff Howe
- Narrated by: James Foster
- Length: 7 hrs and 48 mins
- Unabridged
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Overall4.5 out of 5 stars 365
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Performance4.5 out of 5 stars 308
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Story4.5 out of 5 stars 308
Today, not only is everything digital getting faster, cheaper, and smaller at an exponential rate, we also have the Internet. When these two revolutions - one in technology and the other in communications - joined, an explosive force was unleashed that changed the very nature of innovation. And with any change, we have seen many strategic blunders and extraordinary learning curves along the way.
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4 out of 5 stars
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Just general advice on how to survive
- By A. Yoshida on 09-01-17
By: Joi Ito, and others
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The Problem of Alzheimer's
- How Science, Culture, and Politics Turned a Rare Disease into a Crisis and What We Can Do About It
- By: Jason Karlawish
- Narrated by: Jason Karlawish, Jonathan Todd Ross
- Length: 13 hrs and 41 mins
- Unabridged
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Overall5 out of 5 stars 35
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Performance4.5 out of 5 stars 27
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Story5 out of 5 stars 27
In 2020, an estimated 5.8 million Americans had Alzheimer’s, and more than half a million died because of the disease and its devastating complications. Sixteen million caregivers are responsible for paying as much as half of the $226 billion annual costs of their care. As more people live beyond their 70s and 80s, the number of patients will rise to an estimated 13.8 million by 2025. Part case studies, part meditation on the past, present and future of the disease, The Problem of Alzheimer's traces Alzheimer’s from its beginnings to its recognition as a crisis.
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5 out of 5 stars
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A must read
- By kara kuntz on 05-20-21
By: Jason Karlawish
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The Gene
- An Intimate History
- By: Siddhartha Mukherjee
- Narrated by: Dennis Boutsikaris
- Length: 19 hrs and 22 mins
- Unabridged
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Overall4.5 out of 5 stars 5,865
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Performance4.5 out of 5 stars 5,149
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Story4.5 out of 5 stars 5,102
The extraordinary Siddhartha Mukherjee has written a biography of the gene as deft, brilliant, and illuminating as his extraordinarily successful biography of cancer. Weaving science, social history, and personal narrative to tell us the story of one of the most important conceptual breakthroughs of modern times, Mukherjee animates the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices.
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5 out of 5 stars
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It's a Wonderful Book
- By JKC on 06-02-16
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Thinking Machines
- The Quest for Artificial Intelligence - and Where It's Taking Us Next
- By: Luke Dormehl
- Narrated by: Gus Brown
- Length: 8 hrs and 12 mins
- Unabridged
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Overall4 out of 5 stars 60
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Performance4.5 out of 5 stars 50
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Story4 out of 5 stars 51
When most of us think about artificial intelligence, our minds go straight to cyborgs, robots, and sci-fi thrillers where machines take over the world. But the truth is that artificial intelligence is already among us. It exists in our smartphones, fitness trackers, and refrigerators that tell us when the milk will expire. In some ways the future people dreamed of at the World's Fair in the 1960s is already here. We're teaching our machines how to think like humans, and they're learning at an incredible rate.
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2 out of 5 stars
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Mostly platitudes with no depth
- By Gary on 03-24-17
By: Luke Dormehl
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The Chaos Imperative
- How Chance and Disruption Increase Innovation, Effectiveness, and Success
- By: Ori Brafman, Judah Pollack
- Narrated by: Drew Birdseye
- Length: 4 hrs and 28 mins
- Unabridged
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Overall4.5 out of 5 stars 63
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Performance4.5 out of 5 stars 57
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Story4.5 out of 5 stars 56
Ori Brafman and management consultant Judah Pollack dramatically demonstrate how even the best and most efficient organizations - from Fortune 500 companies to today's US Army - can become more innovative by allowing a little unstructured space and "contained chaos" into their planning and decision-making. Through their consulting work, they realized that while structure and hierarchy are essential both in large corporations and small groups, too much of either can stifle creativity.
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5 out of 5 stars
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a must read!!
- By Kelly Pavich on 05-26-19
By: Ori Brafman, and others
What listeners say about The Code Breaker
Average customer ratingsReviews - Please select the tabs below to change the source of reviews.
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Overall5 out of 5 stars
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Performance5 out of 5 stars
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Story5 out of 5 stars
- Mark T Ryan
- 10-14-23
RNA explained
More than a history lesson, a story that should be universally understood by as many people as possible.
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