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Investigating the Human Genome: Insights into Human Variation and Disease Susceptibility | [Moyra Smith]

Investigating the Human Genome: Insights into Human Variation and Disease Susceptibility

Leading medical genetics scholar Moyra Smith reviews current prospects and progress in medical genetics and genomics, arising from the growth of gene mapping and human genome sequencing. She addresses recent investigations into human origins, migrations, and diversity; psychiatric diseases; Alzheimer's, Parkinsonism, and ALS; protein misfolding; gene-environment interactions; mRNA; epigenetics; and much more.
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Publisher's Summary

Leading medical genetics scholar Moyra Smith reviews current prospects and progress in medical genetics and genomics, arising from the growth of gene mapping and human genome sequencing. She addresses recent investigations into human origins, migrations, and diversity; psychiatric diseases; Alzheimer's, Parkinsonism, and ALS; protein misfolding; gene-environment interactions; mRNA; epigenetics; and much more.

©2011 Moyra Smith (P)2011 Audible, Inc.

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    Conrad Halling Somerville, MA 11-23-11
    Conrad Halling Somerville, MA 11-23-11 Member Since 2008

    Conrad Halling

    HELPFUL VOTES
    30
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    10
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    1
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    "Written for Experts in Human Genomics"

    I expected this book to be aimed at the scientifically aware public, but instead this book seems to be written for genomics researchers. People without training in molecular biology will find this book difficult to understand.

    Unfortunately, this book is not very good even for genomics researchers. Although the information is up to date, it is presented without much organization, background, or context, and the author makes heavy use of scientific jargon without much explanation.

    The narrator, Karen White, tries hard, but her delivery is halting, she mispronounces some words (e.g., kilobase, polymerase, etiology), and she sounds as if she doesn't understand what she's reading.

    7 of 8 people found this review helpful
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  • l
    2/24/15
    Overall
    Performance
    Story
    "Terminologies and not enough explanation"

    I would like to know the author's target audience. It feels like the author is throwing research paper abstracts at readers. Normally, that's the beginning of a book. Then explanations would follow. Author did not appear to have interviewed anyone to create this book. I would recommend the author to check out nessa Carey's 'epigenetic revolution'. Here is a great example for readers who would like to learn and not a total scientific novice. there were lots of terms but the concept were explained very well. If I haven't read her book, I would have no idea what you are talking about related to epigenetic. She explained what is imprinting. Explained with how experiment were done to prove the point. Unfortunately your book only mentioned the fact or the results. Lots of paragraphs just says ' xxx et al, demonstrated this and that'. This is really not the most interesting or explanatory about a topic.
    Rather disappointed about this book. The topic is so interesting in itself

    Your book is too clinical to layman and yet it is not in depth enough as a text book. I hope you can produce a better book next time with these in mind perhaps.

    0 of 0 people found this review helpful
  • Athula
    Abingdon, United Kingdom
    5/11/12
    Overall
    "How about listening to et. al. all the time"

    Funnily enough, I have opted to read (listen?) the audio version of this book drung my long drives. It is a resource of anecdotal evidence rather than a "popular science book" (it is funny to hear et. al. all the time -- the audio book producer and the reader must be dumb -- in the audio version ingenuity is to convert the claptrap on the paper version to a storey). 10% of the book is readable/listenable, rest are probably useful as a reference list (to look up when physically turning the pages of the book). It does update you though.

    0 of 1 people found this review helpful

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