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Breaking Through
- My Life in Science
- Narrated by: Eva Magyar
- Length: 11 hrs and 3 mins
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Publisher's summary
A powerful memoir from Katalin Karikó, winner of the 2023 Nobel Prize in Physiology or Medicine, whose decades-long research led to the COVID-19 vaccines
“Katalin Karikó’s story is an inspiration.”—Bill Gates
“Riveting . . . a true story of a brilliant biochemist who never gave up or gave in.”—Bonnie Garmus, author of Lessons in Chemistry
A KIRKUS REVIEWS BEST BOOK OF THE YEAR
Katalin Karikó has had an unlikely journey. The daughter of a butcher in postwar communist Hungary, Karikó grew up in an adobe home that lacked running water, and her family grew their own vegetables. She saw the wonders of nature all around her and was determined to become a scientist. That determination eventually brought her to the United States, where she arrived as a postdoctoral fellow in 1985 with $1,200 sewn into her toddler’s teddy bear and a dream to remake medicine.
Karikó worked in obscurity, battled cockroaches in a windowless lab, and faced outright derision and even deportation threats from her bosses and colleagues. She balked as prestigious research institutions increasingly conflated science and money. Despite setbacks, she never wavered in her belief that an ephemeral and underappreciated molecule called messenger RNA could change the world. Karikó believed that someday mRNA would transform ordinary cells into tiny factories capable of producing their own medicines on demand. She sacrificed nearly everything for this dream, but the obstacles she faced only motivated her, and eventually she succeeded.
Karikó’s three-decade-long investigation into mRNA would lead to a staggering achievement: vaccines that protected millions of people from the most dire consequences of COVID-19. These vaccines are just the beginning of mRNA’s potential. Today, the medical community eagerly awaits more mRNA vaccines—for the flu, HIV, and other emerging infectious diseases.
Breaking Through isn’t just the story of an extraordinary woman. It’s an indictment of closed-minded thinking and a testament to one woman’s commitment to laboring intensely in obscurity—knowing she might never be recognized in a culture that is driven by prestige, power, and privilege—because she believed her work would save lives.
Critic reviews
“A riveting testament to resilience and the power of unwavering belief, Breaking Through charts an inspirational journey from growing up in postwar communist Hungary to transforming the world with mRNA.”—Jennifer Doudna, Nobel Prize laureate in chemistry and author of A Crack in Creation
“Katalin Karikó’s story is an inspiration. Anyone who has ever doubted that science, innovation, and persistence can change the world should read this book.”—Bill Gates, #1 New York Times bestselling author of How to Avoid a Climate Disaster
“Karikó’s proven recipe (from the creative Hungarian kitchen) for a breakthrough in science: Start with an insatiable curiosity in education and research. Then, for a few decades, look for gaps in knowledge; work hard for years to fill some of them; don’t give up because of difficulties or circumstances; and, finally, seize the opportunity to help solve one painful problem of humanity, thereby opening new horizons for the future of medicine. Bon appétit, enjoy your sweets!”—Ernő Rubik, inventor of the Rubik’s Cube and author of Cubed
“Katalin Karikó’s remarkable life story, which incidentally began not far from where I spent my childhood, inspires us not to be held back even in the face of severe difficulties. It encourages us to stay strong and follow through with important ideas that can change the world.”—Stefan Hell, Nobel Prize laureate in chemistry
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Trace of Doubt
- By: Samantha Weinberg
- Narrated by: Samantha Weinberg
- Length: 4 hrs and 29 mins
- Original Recording
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In the summer of 1985, a brilliant young British DNA scientist Helena Greenwood is found murdered in her front garden in a quiet suburb in California. The police believe they know the killer’s identity but there’s no evidence against him, and the only thing linking him to the crime is the fact he’d been charged with sexually assaulting Helena just a few months previously.
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Frustrating
- By Amazon Customer on 01-28-24
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Going Infinite
- The Rise and Fall of a New Tycoon
- By: Michael Lewis
- Narrated by: Michael Lewis
- Length: 8 hrs and 56 mins
- Unabridged
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Overall
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Performance
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Story
When Michael Lewis first met him, Sam Bankman-Fried was the world’s youngest billionaire and crypto’s Gatsby. CEOs, celebrities, and leaders of small countries all vied for his time and cash after he catapulted, practically overnight, onto the Forbes billionaire list. Who was this rumpled guy in cargo shorts and limp white socks, whose eyes twitched across Zoom meetings as he played video games on the side? In Going Infinite Lewis sets out to answer this question, taking listeners into the mind of Bankman-Fried.
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really expected more rigor from Michael Lewis
- By Wowhello on 10-04-23
By: Michael Lewis
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Elvis and Me
- By: Priscilla Beaulieu Presley
- Narrated by: Priscilla Beaulieu Presley
- Length: 7 hrs and 30 mins
- Unabridged
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The inspiration for the major motion picture Priscilla directed by Sofia Coppola, this New York Times best seller reveals the intimate story of Elvis Presley and Priscilla Presley, told by the woman who lived it.
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What a story!
- By Pen Name on 08-28-22
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The Demon Next Door
- By: Bryan Burrough
- Narrated by: Steve White
- Length: 2 hrs and 45 mins
- Unabridged
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Performance
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Story
Best-selling author Bryan Burrough recently made a shocking discovery: The small town of Temple, Texas, where he had grown up, had harbored a dark secret. One of his high school classmates, Danny Corwin, was a vicious serial killer. In this chilling tale, Burrough raises important questions of whether serial killers can be recognized before they kill or rehabilitated after they do. It is also a story of Texas politics and power that led the good citizens of the town of Temple to enable a demon who was their worst nightmare.
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Odd narration choice
- By Amanda Fredericks on 03-08-19
By: Bryan Burrough
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Genghis Khan and the Making of the Modern World
- By: Jack Weatherford
- Narrated by: Jonathan Davis, Jack Weatherford
- Length: 14 hrs and 20 mins
- Unabridged
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Overall
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Performance
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Story
The Mongol army led by Genghis Khan subjugated more lands and people in 25 years than the Romans did in 400. In nearly every country the Mongols conquered, they brought an unprecedented rise in cultural communication, expanded trade, and a blossoming of civilization.
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Golden Horde/Platinum Listen
- By Cynthia on 12-11-13
By: Jack Weatherford
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Hold Fast
- The Unadulterated Story of the World’s Most Scandalous Website
- By: Trevor Aaronson, Sam Eifling, Michael Mooney
- Narrated by: Trevor Aaronson, Sam Eifling, Michael Mooney
- Length: 7 hrs and 40 mins
- Original Recording
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Hold Fast is the uncompromising story of Backpage.com, the world’s most scandalous website, and the rise and fall of alternative weekly newspapers nationwide.
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An amazing, crazy ride. Highly recommend.
- By Tara N on 04-17-24
By: Trevor Aaronson, and others
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The Debutante
- By: Jon Ronson
- Narrated by: Jon Ronson
- Length: 3 hrs and 11 mins
- Original Recording
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Overall
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Performance
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Story
Thirty years ago, award-winning journalist Jon Ronson stumbled on the mystery of Carol Howe—a charismatic, wealthy former debutante turned white supremacist spokeswoman turned undercover informant. In 1995, Carol was spying on Oklahoma’s neo-Nazis for the government just when Timothy McVeigh blew up a federal building in Oklahoma City, killing 168 people.
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Interesting but not compelling
- By Gail Jester on 04-15-23
By: Jon Ronson
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Sorry for Your Loss
- By: Michael Cruz Kayne
- Length: 1 hr and 23 mins
- Original Recording
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Overall
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Performance
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Story
A sidesplitting, heartrending look at life—and death. This powerfully personal production, recorded live from the Minetta Lane Theatre, cuts through the platitudes, directly reaching out to anyone who has ever experienced loss—or will. So...everyone.
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A Must Listen for the Grieving
- By Chris on 09-25-23
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The Autobiography of Malcolm X
- As Told to Alex Haley
- By: Malcolm X, Alex Haley
- Narrated by: Laurence Fishburne
- Length: 16 hrs and 52 mins
- Unabridged
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Overall
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Performance
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Story
Experience a bold take on this classic autobiography as it’s performed by Oscar-nominated Laurence Fishburne. In this searing classic autobiography, originally published in 1965, Malcolm X, the Muslim leader, firebrand, and Black empowerment activist, tells the extraordinary story of his life and the growth of the Human Rights movement. His fascinating perspective on the lies and limitations of the American dream and the inherent racism in a society that denies its non-White citizens the opportunity to dream, gives extraordinary insight into the most urgent issues of our own time.
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Audible Masterpiece
- By Phoenician on 09-10-20
By: Malcolm X, and others
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French & Saunders Titting About (Series 5)
- By: Dawn French, Jennifer Saunders
- Narrated by: Dawn French, Jennifer Saunders
- Length: 3 hrs and 1 min
- Original Recording
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Overall
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Performance
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Story
Once again, the legendary comedy duo unearth six vitally important subjects... and then tit about about them. From surviving on a desert island to being eaten by a cardboard crocodile, Dawn and Jennifer will entertain, inform and thoroughly tit about for your pleasure. (Batteries not included.)
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Please do more
- By Mr P Ellerington on 04-23-24
By: Dawn French, and others
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The Run of His Life
- The People v. O.J. Simpson
- By: Jeffrey Toobin
- Narrated by: Stephen Bel Davies
- Length: 18 hrs and 46 mins
- Unabridged
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Overall
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Performance
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Story
The definitive account of the O. J. Simpson trial, The Run of His Life is a prodigious feat of reporting that could have been written only by the foremost legal journalist of our time. First published less than a year after the infamous verdict, Jeffrey Toobin's nonfiction masterpiece tells the whole story, from the murders of Nicole Brown Simpson and Ronald Goldman to the ruthless gamesmanship behind the scenes of "the trial of the century".
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Fear and Loathing in Los Angeles
- By Cynthia on 05-24-16
By: Jeffrey Toobin
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Two Women Walk into a Bar
- By: Cheryl Strayed
- Narrated by: Cheryl Strayed
- Length: 51 mins
- Unabridged
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Overall
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Performance
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Story
Twenty-one years after Cheryl Strayed set off on the Pacific Crest Trail to heal from the death of her beloved mother, Cheryl’s mother-in-law, Joan, is given weeks to live. As she and her husband help see Joan through her final days, Cheryl reckons with their complicated relationship, determined to connect with a woman who both showed her love and (sometimes hilariously) held her at a distance. Cheryl reflects on their two decades together as she comes to a deeper understanding of the secrets and sorrows in Joan’s complicated past.
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Cheryl tells a great story!
- By Amazon Customer on 01-01-24
By: Cheryl Strayed
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George Orwell: The Man and the Mind Behind 1984
- By: Michael Shelden, The Great Courses
- Narrated by: Michael Shelden
- Length: 2 hrs and 13 mins
- Original Recording
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Overall
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Performance
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Story
In George Orwell: The Man and the Mind Behind 1984, Professor Michael Shelden will show you how 1984 presents a plausible reality of thought control and totalitarian power that feels contemporary even as it reflects its own time.
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Creating Big Brother
- By Gilbert M. Stack on 04-19-24
By: Michael Shelden, and others
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How to be a great online searcher, demonstrated with step-by-step searches for answers to a series of intriguing questions (for example, "Is that plant poisonous?"). We all know how to look up something online by typing words into a search engine. We do this so often that we have made the most famous search engine a verb: We Google it - "Japan population" or "Nobel Peace Prize" or "poison ivy" or whatever we want to know. But knowing how to Google something doesn't make us search experts; there's much more we can do to access the massive collective knowledge available online.
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Great Communication Tips for Business Leaders
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difficult listen
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Breaking Through
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At the age of 14, Francisco Jiménez, together with his older brother Roberto and his mother, are caught by la migra. Forced to leave their home, the entire family travels all night for 20 hours by bus, arriving at the U.S. and Mexican border in Nogales, Arizona. In the months and years that follow, Francisco, his mother and father, and his seven brothers and sister not only struggle to keep their family together, but also face crushing poverty, long hours of labor, and blatant prejudice.
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Continues The Life Of The Author
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Lab Girl
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Acclaimed scientist Hope Jahren has built three laboratories in which she's studied trees, flowers, seeds, and soil. Her first book might have been a revelatory treatise on plant life. Lab Girl is that, but it is also so much more. Because in it, Jahren also shares with us her inspiring life story, in prose that takes your breath away.
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A paradigm-shifting perspective on plant life
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The Worlds I See
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The moving memoir of a scientist coming of age as an immigrant in America who finds her calling at the forefront of the AI revolution.
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A story of humanism and science
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Finding the Mother Tree
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Suzanne Simard is a pioneer on the frontier of plant communication and intelligence; her TED talks have been viewed by more than 10 million people worldwide. In this, her first book, now available in audio, Simard brings us into her world, the intimate world of the trees, in which she brilliantly illuminates the fascinating and vital truths—that trees are not simply the source of timber or pulp, but are a complicated, interdependent circle of life.
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Couldn't finish, will try the hard copy
- By primrose on 07-22-21
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Empireworld
- How British Imperialism Shaped the Globe
- By: Sathnam Sanghera
- Narrated by: Homer Todiwala
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2.6 billion people are inhabitants of former British colonies. The empire's influence upon the quarter of the planet it occupied, and its gravitational influence upon the world outside it, has been profound: from the spread of Christianity by missionaries to the shaping international law. Even today, 1 in 3 people drive on the left hand side of the road, an artifact of the British empire. Yet Britain's idea of its imperial history and the world's experience of it are two very different things. Empireworld explores the ways in which British Empire has come to shape the modern world.
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What listeners say about Breaking Through
Average customer ratingsReviews - Please select the tabs below to change the source of reviews.
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- Rahil Ghiasvand
- 03-24-24
Inspiring
As a newbie scientist and first Gen woman it was inspiring to hear her story.
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- Jacob Rios
- 10-29-23
a must listen
this book is a must listen. it’s so inspirational and a lesson for how life should be lived.
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- José
- 01-10-24
Inspiring
Kaitlin's memoirs go beyond her major scientific advances to tell of her search for the unknown and her determination and resilience to find it, even without knowing that doing so would save millions of lives. One of the most inspiring stories I have read, but at the same time it reveals how there is a lot to do to support talent, especially women.
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- Linda Hart
- 11-21-23
Remarkable and inspiring story of grit and perseverance
Remarkable and inspiring story of grit and perseverance. Humanity should be forever grateful. Made me wonder how many researchers, particularly women, who quit before seeing the fruits of their labor because of poor leadership in their labs. The reader's accent created the belief that the book was delivered in the author's voice.
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Overall
- Kenny Stein
- 02-01-24
great book! must read!
The book is great, read it.
I personally liked the reader, she has a heavy accent, just know that.
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- Z. Belle
- 01-05-24
Great read
Dr Kariko is a dedicated, hardworking scientist whose drive and commitment to research is incredibly inspirational.
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- Michael Divricean
- 11-04-23
The most beautiful book
This is the best book I read in years!! Thank you Katalin Kariko for never giving up
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- Cathy
- 11-26-23
The power of curiosity, tenacity and integrity in Science.
Dr. Karikó’s description of her quest for knowledge is personal, candid and perspicacious. She is intensely driven by this quest and not the science gamesmanship which is so prevalent in academic institutions.
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- Amazon Kunde
- 04-22-24
Honest, encouraging and completely gripping
There is no way not to inspire by her. A story of determination and following what you believe in/experimenting, even though you’re not sure what it will bring you in the end. It is necessary for all to read, not just for woman in science.
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- Amazon Customer
- 11-08-23
Excellent book!
Excellent book! Read it. Wish everyone could read this book. It is a story of grit.
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