On May 10, 1998, biologist Craig Venter, director of the Institute for Genomic Research, announced that he was forming a private company that within three years would unravel the complete genetic code of human life, seven years before the projected finish of the U.S. government's Human Genome Project. Venter hoped that by decoding the genome ahead of schedule, he would speed up the pace of biomedical research and save the lives of thousands of people. He also hoped to become very famous and very rich. Calling his company Celera (from the Latin for "speed"), he assembled a small group of scientists in an empty building in Rockville, Maryland, and set to work.
At the same time, the leaders of the government program, under the direction of Francis Collins, head of the National Human Genome Research Institute at the National Institutes of Health, began to mobilize an unexpectedly unified effort to beat Venter to the prize, knowledge that had the potential to revolutionize medicine and society.
The stage was set for one of the most thrilling, and important, dramas in the history of science. The Genome War is the definitive account of that drama: the race for the greatest prize biology has had to offer, told by a writer with exclusive access to Venter's operation from start to finish. It is also the story of how one man's ambition created a scientific Camelot where, for a moment, it seemed that the competing interests of pure science and commercial profit might be gloriously reconciled, and the national repercussions that resulted when that dream went awry.
©2004 James Shreeve; (P)2004 Random House, Inc., Random House Audio, a division of Random House, Inc.
"Shreeve delivers commendably clear discourse on techno-molecular obstacles to sequencing DNA, topped with the vivid drama of Celera's mastery of the problems it encountered in doing so. Shreeve's intimate book is a crucial addition to the history of a major scientific fracas." (Booklist)
I learned a lot about competing interests between the public and private sectors. The book showed how typical scientists think, and how one scientist, Venter, struggled to reconcile his scientific mentality with business concerns. My criterion for a good book is one that I devote all of my free time to until it is finished, and this book fell under that category. I had the audio abridged version and finished it within a week. Recommended!
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