Sax presents evidence in a "hit or miss" way. Some of what he has to say is well supported in the literature (e.g., girls lose confidence more quickly than do boys), while other statements are presented without any evidence. When Sax does present studies, he never tells us the number of subjects in any given study nor whether the subjects were selected randomly or other ways of controlling experiments (including keeping subjects from behaving in ways they perceive the experimenter wants them to behave); what is more, the "findings" are presented as if all subjects behaved in a certain way, which is surprising, given that most experiments tell us about likelihood, not certainty. A great deal of the evidence Sax presents is based on studies of animals, showing his implicit assumption that humans evolved from and therefore behave like primates. Unfortunately, Sax does not explain reasons why the reader should accept the analogies. He often presents some study of primates or other animals, then extends a generalized claim about females and males or about human females and males specifically. It ends up casting doubt on everything he says. Nor does Sax make a distinction most scientists make: gender is a sociocultural phenomenon, and sex biological.
This is not to say that gender does not matter nor that Sax gives bad advice. It is just that the advice pretends to be drawn from scientific evidence or as unsupported extensions of other arguments (e.g., boys get a thrill from violent video games; Sax himself played two different games; therefore you should accept his experience with the games as representative of all people's experience and further, you should not allow your child to play the type where it's okay to kill off civilians at will -- note that he also ignores alternative explanations for the "thrill," such as simply violating social norms). Perhaps there are numerous footnotes in the text version that an audiobook does not present.
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